Aceclofenac 100 mg Tablet Use, Indication, Side Effects, Dosage, Mechanism of Action, Price, Contra-Indications, Drug Interactions..

HETROFEN 100 Tablet

Each HETROFEN 100 tablet contains 100 mg of Aceclofenac, a nonsteroidal anti-inflammatory drug (NSAID)

Aceclofenac 100 Tablet belongs to a group of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs). It is used for short term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.

Uses and Indications:
HETROFEN 100 is prescribed for:

• Osteoarthritis
• Rheumatoid arthritis
• Ankylosing spondylitis
• It helps alleviate pain and inflammation associated with these conditions.

Mechanism of Action:
Aceclofenac inhibits cyclooxygenase (COX), with a preference for COX-2, reducing the production of prostaglandins that cause pain and inflammation. Additionally, it stimulates the synthesis of glycosaminoglycans (GAGs), which are essential for cartilage repair.

Dosage:
Typically, 100 mg taken orally twice daily. For patients with liver impairment, an initial dose of 100 mg per day is recommended.

Side Effects:
Common side effects include:

• Indigestion
• Heartburn
• Dyspepsia
• Diarrhea
• Nausea
• Abdominal pain
• Flatulence

Serious side effects may involve gastrointestinal bleeding, kidney or liver issues, and cardiovascular events.

Contraindications:
HETROFEN 100 should not be used by individuals with:

• Hypersensitivity to Aceclofenac or other NSAIDs
• Active or history of gastrointestinal bleeding
• Severe renal or hepatic impairment
• Third trimester of pregnancy

Use with caution in patients with a history of peptic ulcers, gastrointestinal disorders, or cardiovascular conditions.

Drug Interactions:
Potential interactions include:

• Increased plasma levels of lithium and digoxin
• Reduced effectiveness of diuretics and antihypertensive drugs
• Enhanced anticoagulant effects
• Increased risk of convulsions when combined with quinolones

Always inform your healthcare provider about all medications you are taking to avoid adverse interactions.

For Use of Registered Medical Practitioner or A Hospital Only

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