Aceclofenac 100 mg, Thiocolchiside 4 mg Tablet Use, Indication, Side Effects, Dosage, Mechanism of Action, Price, Contra-Indications, Drug Interactions ...

HETROFEN TC Tablet

Aceclofenac 100 mg,Thiocolchiside 4 mg Film Coated Tablets

HETROFEN TC Tablet is a combination medication that contains Aceclofenac (100 mg) and Thiocolchicoside (4 mg). It is used primarily for pain and inflammation management in musculoskeletal disorders. 

Use & Indications:

HETROFEN TC is used for:

• Pain and Inflammation: It is commonly used in conditions like osteoarthritis, rheumatoid arthritis, and spondylitis.

• Musculoskeletal Conditions: It's effective in treating muscle spasms, back pain, and other musculoskeletal disorders due to its anti-inflammatory and muscle relaxant properties.

• Post-Surgical Pain: Often prescribed after surgery to reduce pain and promote mobility.

Mechanism of Action:

1. Aceclofenac (100 mg):

   • Class: Non-Steroidal Anti-Inflammatory Drug (NSAID)

   • Action: Aceclofenac works by inhibiting cyclooxygenase enzymes (COX-1 and COX-2). These enzymes are responsible for producing prostaglandins, which are chemicals that cause pain, inflammation, and fever. By reducing the production of prostaglandins, Aceclofenac helps to alleviate pain and reduce inflammation.

2. Thiocolchicoside (4 mg):

   • Class: Muscle Relaxant

   • Action: Thiocolchicoside acts on the central nervous system to reduce muscle spasms by inhibiting spinal reflexes. It helps in relaxing the muscles and reducing stiffness.

Dosage:

• Adults: Typically, one tablet of HETROFEN TC is taken twice daily (morning and evening).

• Maximum Dose: The maximum recommended dose is one tablet twice a day, but the dosage may vary depending on the severity of the condition and the physician’s recommendation.

Side Effects:

Common side effects can include:

• Gastrointestinal Issues: Nausea, dyspepsia (indigestion), abdominal pain, or diarrhea.

• Headache or dizziness

• Rashes or skin reactions

• Liver enzyme abnormalities in rare cases

• Renal issues (kidney problems) if used for prolonged periods or in high doses.

Serious side effects (less common):

• Gastrointestinal bleeding (due to NSAID action)

• Severe allergic reactions like swelling, shortness of breath, or anaphylaxis.

• Muscle weakness or fatigue due to thiocolchicoside.

If any severe side effects occur, contact a healthcare professional immediately.

Contraindications:

HETROFEN TC should not be used in the following conditions:

• Peptic Ulcer Disease or GI Bleeding

• Severe Hepatic (Liver) Dysfunction

• Severe Renal (Kidney) Impairment

• Hypersensitivity to Aceclofenac, Thiocolchicoside, or other NSAIDs

• Pregnancy (especially in the third trimester)

• Breastfeeding (use only if necessary and under medical supervision)

• Children (not recommended in pediatric patients)

Drug Interactions:

Some drugs that may interact with HETROFEN TC:

1. Anticoagulants (e.g., warfarin): May increase the risk of bleeding.

2. Other NSAIDs or Steroids: Use with caution as they can increase the risk of gastrointestinal bleeding or ulceration.

3. Diuretics: May impair renal function when combined with Aceclofenac.

4. Lithium: Aceclofenac may increase the levels of lithium in the blood.

5. Methotrexate: Increased risk of toxicity when combined with NSAIDs.

6. Antihypertensive drugs: NSAIDs may reduce the effectiveness of blood pressure medications.

For Use of Registered Medical Practitioner or A Hospital Only

GREEN CROSS REMEDIES