Itraconazole 200 mg Use, Indication, Side Effects, Dosage, Mechanism of Action, Price, Contra-Indications, Drug Interactions...

TRACOLUS 200 Capsule (Itraconazole 200 mg)

TRACOLUS 200 Capsules contain 200 mg of itraconazole, a synthetic triazole antifungal agent used to treat various fungal infections.

Uses and Indications:

Itraconazole is prescribed for:

• Dermatophytoses

• Onychomycoses

• Tinea versicolor

• Cutaneous candidiasis

• Oropharyngeal candidiasis

• Vulvovaginal candidiasis

• Chronic mucocutaneous candidiasis

• Oculomycoses

• Systemic mycosis

Dosage:

The typical dosage varies based on the infection type:

• Onychomycosis: 200 mg daily for 3-5 months or 400 mg daily for one week per month over three consecutive months.

• Candidiasis of Nail: 200 mg daily for 3-5 months or 400 mg daily for one week per month over three consecutive months.

• Tinea Capitis: 100 mg once daily for 4 weeks.

• Tinea Corporis/Tinea Cruris: 100 mg daily for 15 days or 200 mg daily for 7 days.

• Mucocutaneous Candidiasis: 200 mg daily for 5-7 days.

• Tinea Pedis: 100 mg daily for 30 days or 200 mg twice daily for 7 days.

• Pityriasis Versicolor (Chronic/Recurrent): 200 mg daily for 7 days.

• Vulvovaginal Candidiasis: 200 mg twice daily for 1 day.

Mechanism of Action:

Itraconazole works by inhibiting the synthesis of ergosterol, a vital component of fungal cell membranes, leading to cell membrane destruction and cessation of fungal growth.

Side Effects:

Common side effects may include:

• Nausea

• Vomiting

• Rash

• Pruritus (itching)

• Vertigo

• Pedal edema (swelling of the feet)

• Depression

• Dizziness

• Loss of libido

• Paresthesia (tingling sensation)

• Impotence

Contraindications:

Itraconazole is contraindicated in individuals with hypersensitivity to azole antifungal.

Drug Interactions:

Itraconazole may interact with:

• Terfenadine

• Astemizole

• Cycloserine

• Digoxin

• Phenytoin

• Oral anticoagulants

• Rifampicin

• H2 antagonists

• Isoniazid (INH)

• Oral hypoglycemic agents

For Use of Registered Medical Practitioner or A Hospital Only

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