ANXO 0.50 Tablet
Alprazolam 0.50 mg Tablet Use, Indication, Side Effects, Dosage, Mechanism of Action, Price, Contra-Indications, Drug Interactions....
ANXO 0.50 Tablet
Composition: Each Uncoated Tablet contains Alprazolam I.P 0.50 mg
Uses and Indications
ANXO 0.50 mg tablet is primarily used for the treatment of the following conditions:
- Generalized Anxiety Disorder (GAD): Used to manage excessive anxiety and worry.
- Panic Disorder: Treatment of panic attacks, often with or without agoraphobia (fear of being in situations where escape might be difficult).
- Short-Term Relief: Used in the short-term management of anxiety symptoms.
- Other Off-label Uses: Sometimes prescribed for other anxiety-related conditions or insomnia.
Mechanism of Action
Alprazolam, the active ingredient in ANXO, is a benzodiazepine. It works by affecting the central nervous system, specifically by enhancing the effect of a neurotransmitter called gamma-aminobutyric acid (GABA). GABA inhibits neural activity, leading to calming effects on the brain, which helps reduce anxiety, muscle tension, and symptoms of panic attacks.
Dosage
The dosage of ANXO should always be determined by a healthcare provider based on the patient's condition and individual response. A typical starting dosage might be:
- For Generalized Anxiety Disorder (GAD): 0.25 to 0.5 mg taken 2-3 times daily.
- For Panic Disorder: The dosage may start at 0.5 mg, 3 times daily, and could be adjusted based on response.
The maximum recommended dose for most adults is 4 mg per day, divided into several doses.
Important Note: Always follow your healthcare provider's recommendations for dosage. Do not increase or decrease the dose without their approval.
Side Effects
Common side effects of Alprazolam (ANXO) can include:
- Drowsiness or sedation
- Dizziness
- Fatigue
- Memory problems or confusion
- Dry mouth
- Appetite changes
- Constipation
Less common but serious side effects may include:
- Severe allergic reactions (rash, itching, swelling, difficulty breathing)
- Mood changes (depression, thoughts of suicide)
- Muscle weakness
- Loss of coordination
- Hallucinations or confusion
If any severe side effects occur, seek medical attention immediately.
Contraindications
ANXO should not be used in the following cases:
- Hypersensitivity to Alprazolam or any other benzodiazepines.
- Severe liver impairment (Cirrhosis or Hepatitis).
- Acute narrow-angle glaucoma.
- Pregnancy: Use during pregnancy is not recommended unless absolutely necessary due to potential risks to the fetus.
- Breastfeeding: Alprazolam may pass into breast milk and could harm a nursing infant.
- Respiratory issues: It should be avoided in people with severe respiratory depression, including sleep apnea.
Drug Interactions
Several medications and substances may interact with Alprazolam (ANXO). Some important interactions include:
- Alcohol: Can increase the sedative effects of Alprazolam, leading to extreme drowsiness, respiratory depression, or even overdose.
- Other CNS Depressants (e.g., opioids, barbiturates, antipsychotics): May enhance sedative effects and increase the risk of respiratory depression.
- Antidepressants: Some antidepressants (e.g., SSRIs, tricyclic antidepressants) may increase the blood levels of Alprazolam, intensifying side effects.
- CYP3A4 Inhibitors: Medications that inhibit the CYP3A4 enzyme (e.g., ketoconazole, itraconazole) can increase Alprazolam's concentration in the body, raising the risk of side effects.
- CYP3A4 Inducers: Medications like carbamazepine or rifampin can lower Alprazolam’s effectiveness by decreasing its concentration in the bloodstream.
Always inform your doctor about all other medications you're taking, including over-the-counter drugs and supplements.
Warnings and Precautions
- Dependence and Withdrawal: Prolonged use of Alprazolam can lead to physical and psychological dependence. Abrupt discontinuation can lead to withdrawal symptoms such as anxiety, agitation, and seizures. It is recommended to taper off the medication gradually under a doctor's guidance.
- Elderly: Caution is advised in older adults as they may be more susceptible to the sedative effects of Alprazolam, increasing the risk of falls and cognitive impairment.
- Driving and Operating Machinery: Since Alprazolam can cause drowsiness and impair coordination, it is advised to avoid driving or performing activities that require full alertness until you know how the medication affects you.
- Mental Health Conditions: Use caution in patients with a history of depression, substance use disorder, or psychosis.
For Use of registered medical practitioner or a hospital only
