Cefixime and Potassium Clavulanate Dry Syrup – ROVIXIM CLAV Dry Syrup

Cefixime and potassium clavulanate dry syrup is a broad-spectrum pediatric antibiotic formulation widely prescribed for the effective treatment of bacterial infections in infants and children. This advanced oral suspension combines a third-generation cephalosporin with a beta-lactamase inhibitor, providing enhanced antibacterial coverage and reducing the risk of resistance.

ROVIXIM CLAV Dry Syrup is developed to deliver reliable therapeutic outcomes with accurate dosing and improved palatability, making it suitable for pediatric use when prescribed by a healthcare professional. Manufactured by Green Cross Remedies, this formulation meets stringent quality standards and supports safe, effective infection management in children.

Product Composition

Each 5 ml of reconstituted dry syrup contains:

• Cefixime – 50 mg
• Clavulanic Acid – 31.25 mg
• Flavoured base q.s.
• Supplied with Water for Injection for reconstitution

Uses of Cefixime and Potassium Clavulanate Dry Syrup

Cefixime and potassium clavulanate oral suspension uses include treatment of a wide range of pediatric bacterial infections, particularly when resistance to single-antibiotic therapy is suspected.

Common uses include:

• Upper and lower respiratory tract infections
• Acute otitis media (ear infections)
• Throat & Tonsil Infections: Tonsillitis and pharyngitis.
• Respiratory Tract Infections: Bronchitis and pneumonia.
• Urinary Tract Infections (UTI)
• Meningitis
• Genito-Urinary Infection
• Septicemia
• Surgical Prophylaxis
• Intra-Abdominal Infection
• Acute bacterial sinusitis
• Skin and soft tissue infections

This combination is often recommended when beta-lactamase–producing bacteria are involved, ensuring broader antimicrobial coverage and improved clinical response.

Indications

ROVIXIM CLAV Dry Syrup is indicated for infections caused by cefixime-sensitive organisms in pediatric patients. It is commonly prescribed for:

• Bronchitis and pneumonia
• ENT infections
• Complicated urinary tract infections
• Gastrointestinal bacterial infections
• Mixed bacterial infections requiring combination therapy

Mechanism of Action

This powerful combination fights infection in two ways:

• Cefixime acts by inhibiting bacterial cell wall synthesis, leading to bacterial cell death. However, certain bacteria produce beta-lactamase enzymes that can inactivate cephalosporins.
• Clavulanic acid neutralizes these enzymes, protecting cefixime from degradation. This synergistic action makes cefixime clavulanic acid dry syrup highly effective against resistant bacterial strains and ensures sustained antibacterial activity.

Dosage:

• Important: The dosage is based on your child's body weight and the severity of the infection. Always follow the pediatrician's instructions precisely.
• Reconstitution: Add the provided sterile water up to the mark on the bottle and shake well to prepare the syrup.
• Use the measuring cup or syringe provided to ensure an accurate dose.
• Complete the entire course of treatment, even if the child starts to feel better, to prevent the infection from recurring.

Dosage and Administration

Cefixime clavulanate dry syrup dosage for children should be strictly determined by a pediatrician based on the child’s age, body weight, severity of infection, and clinical response.

General guidelines:

• Administer twice daily or as prescribed
• Shake well before each use
• Measure dose using the provided measuring cup
• Preferably administer after food to reduce gastric discomfort

Do not exceed the recommended dose or duration.

Side Effects

Most children tolerate this medication well. However, cefixime clavulanic acid syrup side effects may include:

• Mild diarrhea
• Nausea or vomiting
• Abdominal discomfort
• Skin rash

Rare allergic reactions may occur. Immediate medical attention is required if swelling of the face, lips, or breathing difficulty is observed.

Contraindications and Precautions

• Contraindicated in patients with known hypersensitivity to cephalosporins or clavulanic acid
• Use with caution in children with a history of gastrointestinal disorders
• Renal impairment may require dose adjustment
• Not recommended without medical supervision

Drug Interactions

• Concomitant use with anticoagulants may increase bleeding risk
• Probenecid may increase cefixime levels
• May reduce the effectiveness of oral vaccines

Always inform the physician about all medications the child is receiving.

Storage Instructions

• Store below 25°C
• Protect from moisture and direct sunlight
• After reconstitution, store as directed and use within the prescribed period
• Keep out of reach of children

Cefixime and Potassium Clavulanate Dry Syrup Price – ROVIXIM CLAV Dry Syrup (MRP):

Expert Advice

• Cefixime 50 mg & Clavulanic Acid 31.25 mg / 5 ml dry syrup should always be administered exactly as prescribed by a qualified healthcare professional.
• Avoid missing doses and do not stop treatment early, even if symptoms improve, as incomplete therapy may lead to recurrence or antibiotic resistance.
• This medication should never be self-medicated or shared between children.
• Ensure adequate hydration during therapy.
• Administer the syrup after meals to minimize stomach upset.
• Discontinue the medicine and seek immediate medical attention if the child develops rash, itching, swelling of the face or mouth, or breathing difficulty. Avoid combining antibiotics without medical advice to ensure safe and effective treatment.

Frequently Asked Questions (FAQs)

What is cefixime and potassium clavulanate dry syrup used for?

• It is used to treat respiratory, ENT, urinary, and skin infections caused by susceptible bacteria in children.

Is this dry syrup safe for infants?

• Yes, when prescribed by a pediatrician and administered at the recommended dosage.

Who is the manufacturer of ROVIXIM CLAV Dry Syrup?

• ROVIXIM CLAV Dry Syrup is manufactured by Green Cross Remedies, a trusted pharmaceutical company in India.

Is this effective against resistant infections?

• Yes, the presence of clavulanic acid helps overcome beta-lactamase–mediated resistance.

ROVIXIM CLAV Dry Syrup by GREEN CROSS REMEDIES is a reliable cefixime and potassium clavulanate dry syrup formulation from a trusted leading antibiotic manufacturer in India. Manufactured in a WHO-GMP certified facility, it ensures consistent quality, proven efficacy, and dependable therapeutic outcomes, making it a preferred choice for healthcare professionals managing pediatric bacterial infections.

Disclaimer:

This information is intended for the use of Registered Medical Practitioners, Hospitals, Medical Stores, Pharma Agencies, Healthcare Professionals, Pharmaceutical Company Field Staff, and Pharmacies Only.

GREEN CROSS REMEDIES