Cefpodoxime 100mg Dry Syrup – SPINXO 100 Dry Syrup
- Cefpodoxime 100mg dry syrup is a widely prescribed third-generation cephalosporin antibiotic used primarily in pediatric patients to manage a broad range of bacterial infections.
- Known for its strong antibacterial coverage and favorable safety profile, this formulation is commonly recommended by healthcare professionals for respiratory, urinary, ear, and skin infections in children.
- SPINXO 100 Dry Syrup contains Cefpodoxime Proxetil 100 mg per 5 ml, supplied as a dry syrup that is reconstituted with water for injection to ensure accurate dosing and enhanced stability.
- Manufactured by Green Cross Remedies, this product is developed following stringent quality standards to deliver consistent therapeutic outcomes in pediatric care.
Composition
Each 5 ml of reconstituted syrup contains:
- Cefpodoxime Proxetil IP equivalent to Cefpodoxime 100 mg
- Flavoured dry syrup base
- Pack Size: 30 ml (to be reconstituted with water for injection)
Uses of Cefpodoxime 100 mg Dry Syrup
Cefpodoxime 100 mg dry syrup is used to treat various bacterial infections caused by susceptible organisms. It is especially preferred in children due to its oral convenience and effective absorption.
Cefpodoxime 100 mg syrup uses include:
- Upper and lower respiratory tract infections
- Ear infections (otitis media)
- Throat and tonsillar infections
- Urinary tract infections (UTIs)
- Skin and soft tissue infections
- Pharyngitis & Tonsillitis
- Typhoid
Indications
Cefpodoxime 100 mg Dry Syrup is indicated for pediatric patients diagnosed with:
- Acute bronchitis and pneumonia
- Pharyngitis and tonsillitis
- Acute otitis media
- Uncomplicated urinary tract infections
- Mild to moderate bacterial skin infections
Mechanism of Action
- Cefpodoxime Proxetil is a prodrug that converts into active cefpodoxime after oral administration.
- It works by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins (PBPs).
- This action weakens the bacterial cell wall, leading to cell lysis and eventual death of the bacteria, thereby effectively clearing the infection.
Dosage and Administration
The Cefpodoxime 100 mg dry syrup dosage for children depends on age, body weight, severity of infection, and clinical response.
- The syrup should be reconstituted with the recommended quantity of water for injection
- Administer exactly as prescribed by a pediatrician
- Typically given once or twice daily
- Best taken with food to improve absorption
Do not exceed the prescribed dose and complete the full course of therapy.
Side Effects
Like all antibiotics, cefpodoxime dry syrup may cause mild and temporary side effects in some children.
Common Cefpodoxime 100 mg syrup side effects:
- Diarrhea
- Nausea or vomiting
- Abdominal discomfort
- Headache
Rare but serious reactions include allergic skin rash, swelling, or breathing difficulty. Immediate medical attention is advised if such symptoms occur.
Contraindications and Precautions
- Known hypersensitivity to cefpodoxime
- Contraindicated in patients with known hypersensitivity to cephalosporins
- Use with caution in children with a history of penicillin allergy
- Monitor renal function in prolonged therapy
- Not recommended for viral infections such as common cold or flu
- Severe renal impairment (creatinine clearance < 30 mL/min)
Parents should inform the doctor about any ongoing medications or medical conditions.
Drug Interactions
Cefpodoxime proxetil syrup 100 mg may interact with:
- Antacids and H2 blockers (may reduce absorption)
- Probenecid (may increase blood levels)
- Nephrotoxic drugs (use cautiously)
Always consult a healthcare professional before combining medications.
Storage Instructions
- Store the dry syrup below 25°C
- After reconstitution, keep refrigerated
- Use the reconstituted syrup within the prescribed time
- Keep out of reach of children
- Shake well before each use
Cefpodoxime 100 mg Dry Syrup Price – SPINXO 100 Dry Syrup (MRP): 178.78
Expert Advice for Cefpodoxime 100 Dry Syrup
- Cefpodoxime 100 mg / 5 ml Dry Syrup should always be administered exactly as prescribed by a healthcare professional.
- Parents should avoid skipping doses or stopping treatment early, even if the child’s symptoms improve. Incomplete antibiotic courses can lead to resistance and recurrence of infection.
- Ensure adequate hydration during therapy and report any unusual side effects promptly.
- The syrup should ideally be given with food to minimize stomach upset.
- Discontinue use and seek immediate medical attention if allergic reactions such as rash, facial swelling, or breathing difficulty occur. Antibiotics should never be self-medicated or shared between children.
Frequently Asked Questions (FAQs)
What is cefpodoxime 100mg dry syrup used for?
- It is used to treat bacterial infections affecting the respiratory tract, ears, throat, urinary tract, and skin in children.
Is SPINXO 100 Dry Syrup safe for children?
- Yes, when used as prescribed. SPINXO 100 Dry Syrup is manufactured by Green Cross Remedies under strict quality standards to ensure safety and efficacy.
How should cefpodoxime dry syrup be given to children?
- It should be given after reconstitution, preferably with food, and strictly according to the pediatrician’s dosage instructions.
Who manufactures SPINXO 100 Dry Syrup?
- SPINXO 100 Dry Syrup is manufactured by Green Cross Remedies, a trusted pharmaceutical company in India.
SPINXO 100 Dry Syrup by Green Cross Remedies is a reliable cefpodoxime 100mg dry syrup formulation from a trusted pediatric antibiotic manufacturer in India. Manufactured in a WHO-GMP certified facility, it ensures consistent quality, proven antibacterial efficacy, and dependable therapeutic outcomes, making it a preferred choice for healthcare professionals in managing pediatric bacterial infections.
Disclaimer:
This information is intended for the use of Registered Medical Practitioners, Hospitals, Medical Stores, Pharma Agencies, Healthcare Professionals, Pharmaceutical Company Field Staff, and Pharmacies Only.
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