Cefpodoxime Proxetil and Potassium Clavulanate Tablets-SPINXO CLAV Tablet

Cefpodoxime proxetil and potassium clavulanate tablets is a widely prescribed oral antibiotic combination used for the effective management of a broad range of bacterial infections.

This combination brings together the proven efficacy of a third-generation cephalosporin with a beta-lactamase inhibitor, helping overcome bacterial resistance and ensuring reliable therapeutic outcomes.

SPINXO CLAV Tablet is formulated to deliver optimal antibacterial coverage against susceptible gram-positive and gram-negative organisms. Each film-coated tablet contains Cefpodoxime Proxetil 200 mg and Clavulanic Acid 125 mg, offering a balanced dose suitable for moderate to severe infections when prescribed by a healthcare professional.

SPINXO CLAV Tablet is a Cefpodoxime Proxetil and Potassium Clavulanate antibiotic combination by Green Cross Remedies, offering broad-spectrum protection against resistant bacterial infections.

Composition

Each Film-Coated SPINXO CLAV Tablet contains:

• Cefpodoxime Proxetil IP – 200 mg
• Clavulanic Acid IP – 125 mg
• Excipients – q.s.
• Colour: As approved

Uses and Indications

Cefpodoxime potassium clavulanate tablets uses include treatment of infections caused by susceptible organisms, such as:

• Upper and lower respiratory tract infections
• Community-acquired pneumonia
• Acute bacterial sinusitis
• Tonsillitis and pharyngitis
• Urinary tract infections
• Skin and soft tissue infections
• Otitis media
• Other bacterial infections: that are susceptible to cefpodoxime and clavulanic acid combination.
• Excellent Coverage Against Gram + Ve And Gram – Ve Pathogens
• Kills Even ESBL Producing Pathogens

Clinicians often recommend this combination where resistance to single-agent antibiotics is suspected or confirmed.

Mechanism of Action

Cefpodoxime Proxetil is a prodrug that converts into its active form, cefpodoxime, after oral administration. It works by inhibiting bacterial cell wall synthesis, leading to bacterial cell death. However, some bacteria produce beta-lactamase enzymes that can inactivate cephalosporins.

Clavulanic acid plays a crucial role by inhibiting these beta-lactamase enzymes. This protective action restores the antibacterial activity of cefpodoxime, making the Cefpodoxime clavulanic acid combination tablet highly effective against resistant strains.

Together, they provide enhanced and sustained antibacterial action.

Dosage and Administration

Cefpodoxime clavulanic acid dosage should be determined by a physician based on the severity of infection, patient age, renal function, and clinical response.

• Typically administered twice daily
• Preferably taken after food to improve absorption and reduce gastric discomfort
• Complete the full prescribed course, even if symptoms improve early

Dose adjustments may be required in patients with renal impairment.

Side Effects

Like all antibiotics, cefpodoxime and potassium clavulanate tablets side effects may occur in some patients, although not everyone experiences them.

Common side effects include:

• Nausea or vomiting
• Diarrhea
• Abdominal discomfort
• Headache

Rare but serious reactions may include allergic reactions, skin rashes, or severe diarrhea. Immediate medical attention is advised if hypersensitivity symptoms appear.

Contraindications and Precautions

• Contraindicated in patients with known hypersensitivity to cephalosporins or clavulanic acid
• Use cautiously in patients with a history of gastrointestinal disease, especially colitis
• Renal and hepatic function monitoring is recommended during prolonged therapy
• Not recommended for self-medication

Drug Interactions

• Concomitant use with anticoagulants may increase bleeding risk
• Probenecid may increase cefpodoxime levels
• Oral contraceptives may show reduced effectiveness

Patients should inform their physician about all ongoing medications before starting therapy.

Storage Instructions

• Store below 25°C
• Protect from moisture and direct sunlight
• Keep out of reach of children
• Do not use after the expiry date

Cefpodoxime Proxetil 200 mg + Clavulanic Acid 125 mg Tablet Price - Spinxo Clav Tablet (MRP) : 215.00

Expert Advice for Cefpodoxime 200 mg, Clavulanic Acid 125 mg Tablet

• Cefpodoxime proxetil and potassium clavulanate tablet should always be taken exactly as prescribed by a healthcare professional.
• Do not skip doses or stop treatment prematurely, even if symptoms improve, as this may lead to incomplete infection control and antibiotic resistance.
• Avoid self-medication and never share antibiotics with others.
• Adequate hydration during therapy is advised. Taking the tablet with food helps reduce stomach upset.
• Discontinue the medicine and consult a doctor immediately if signs of allergy such as rash, itching, facial swelling, or breathing difficulty occur.
• Alcohol consumption should be avoided during treatment to minimize side effects and ensure optimal efficacy.

Frequently Asked Questions (FAQs) - SPINXO CLAV Tablet

What are Cefpodoxime 200 mg clavulanic acid uses?

• This combination is used to treat respiratory, urinary, skin, and ENT infections caused by susceptible bacteria.

Is SPINXO CLAV Tablet suitable for resistant infections?

• Yes, the presence of clavulanic acid helps counter beta-lactamase-producing bacteria, improving effectiveness.

 Who is a reliable Cefpodoxime clavulanate manufacturer in India?

• Green Cross Remedies is a trusted Indian pharmaceutical company manufacturing SPINXO CLAV Tablet under stringent quality standards.

Can this tablet be taken on an empty stomach?

• It is recommended to take it after food to improve tolerance and absorption.

Cefpodoxime proxetil and potassium clavulanate tablets, marketed as SPINXO CLAV Tablet, is a clinically reliable antibiotic formulation manufactured by Green Cross Remedies, a reputed pharmaceutical company in India. Designed to meet modern antimicrobial challenges, SPINXO CLAV Tablet combines potent efficacy with consistent quality, making it a dependable choice for healthcare professionals managing bacterial infections.

SPINXO CLAV by GREEN CROSS REMEDIES is a reliable Cefpodoxime Proxetil 200 mg and Clavulanic Acid 125 mg formulation from a trusted Cefpodoxime clavulanate manufacturer in India. Manufactured in a WHO-GMP certified facility, it ensures consistent quality, proven efficacy, and dependable therapeutic outcomes, making it a preferred choice for clinicians treating a wide range of bacterial infections.

Disclaimer:

This information is intended for the use of Registered Medical Practitioners, Hospitals, Medical Stores, Pharma Agencies, Healthcare Professionals, Pharmaceutical Company Field Staff, and Pharmacies Only.

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