Cefpodoxime Syrup – Spinxo Dry Syrup

Cefpodoxime syrup is a widely prescribed oral antibiotic formulation used mainly in pediatric patients to treat a variety of bacterial infections.Belonging to the third-generation cephalosporin class, cefpodoxime is known for its broad-spectrum antibacterial activity, good tolerability, and convenient oral administration.It is commonly recommended by pediatricians for respiratory, ear, urinary, and skin infections caused by susceptible bacteria.

SPINXO Dry Syrup is a clinically trusted formulation containing Cefpodoxime Proxetil 50 mg per 5 ml, supplied as a dry syrup that is reconstituted with water for injection before use.

Manufactured by Green Cross Remedies, this product is developed under strict quality control systems to ensure safety, stability, and consistent therapeutic effectiveness in children.

Composition

Each 5 ml of reconstituted syrup contains:

• Cefpodoxime Proxetil IP equivalent to Cefpodoxime 50 mg
• Flavoured dry syrup base
• Pack Size: 30 ml (to be reconstituted with water for injection)

Uses of Cefpodoxime Syrup

Cefpodoxime syrup is primarily used to treat bacterial infections in pediatric patients. Its oral liquid formulation makes it easier to administer to children who may have difficulty swallowing tablets.

Cefpodoxime syrup uses include:

• Upper and lower respiratory tract infections
• Ear infections such as otitis media
• Throat infections including tonsillitis and pharyngitis
• Urinary tract infections
• Skin and soft tissue infections
• Pneumonia.
• Gonorrhea (uncomplicated)
• Typhoid

The syrup cefpodoxime formulation ensures effective drug absorption and reliable antibacterial action when used as prescribed.

Indications

SPINXO Dry Syrup is indicated for the treatment of mild to moderate infections caused by cefpodoxime-sensitive organisms, including:

• Acute bronchitis and community-acquired pneumonia
• Pharyngitis and tonsillitis
• Skin and soft tissue infections
• Acute otitis media
• Uncomplicated urinary tract infections

Mechanism of Action

• Cefpodoxime Proxetil is an oral prodrug that converts into active cefpodoxime after absorption in the gastrointestinal tract.
• The active drug inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs).
• This weakens the bacterial cell wall, leading to cell rupture and bacterial death. Its stability against many beta-lactamases makes cefpodoxime dry syrup effective against a broad range of gram-positive and gram-negative bacteria.

Dosage and Administration

The cefpodoxime dry syrup dosage depends on the child’s age, body weight, severity of infection, and clinical condition.

• Reconstitute the dry syrup with the recommended quantity of water for injection
• Shake well before every dose
• Administer as prescribed by a pediatrician
• Usually given once or twice daily
• Preferably taken with food to enhance absorption and reduce gastric discomfort

Parents should ensure the full prescribed course is completed, even if symptoms improve early.

Side Effects

Cefpodoxime syrup is generally well tolerated when used correctly. However, some children may experience mild side effects.

Common side effects include:

• Diarrhea
• Nausea or vomiting
• Abdominal pain
• Headache

Rarely, allergic reactions such as skin rash, itching, swelling of the face or lips, or breathing difficulty may occur and require immediate medical attention.

Contraindications and Precautions

• Contraindicated in patients with known hypersensitivity to cefpodoxime or other cephalosporins
• Use with caution in children with a history of severe penicillin allergy
• Caution advised in patients with renal impairment
• Not effective against viral infections such as common cold or flu

Always inform the doctor about any existing medical conditions before starting therapy.

Drug Interactions

Cefpodoxime proxetil 50mg dry syrup may interact with:

• Antacids and acid-suppressing agents (can reduce absorption)
• Probenecid (may increase cefpodoxime levels)
• Nephrotoxic drugs (monitor renal function if used together)

Consult a healthcare professional before administering other medicines alongside cefpodoxime dry syrup.

Storage Instructions

• Store the dry syrup below 25°C
• Protect from moisture and direct sunlight
• After reconstitution, store in a refrigerator
• Use the reconstituted syrup within the recommended period
• Keep out of reach of children

Cefpodoxime 50mg Dry Syrup Price – Spinxo Dry Syrup (MRP): 126.28

Expert Advice

• Cefpodoxime Proxetil 50 mg/5 ml Dry Syrup should always be administered exactly as prescribed by a healthcare professional.
• Parents should avoid skipping doses or discontinuing therapy prematurely, even if the child’s symptoms improve, as this may lead to incomplete infection clearance and antibiotic resistance.
• Antibiotics should never be self-medicated or shared.
• Adequate hydration during treatment is recommended.
• The syrup should ideally be taken with food to minimize stomach upset.
• Discontinue the medicine and seek immediate medical attention if symptoms such as skin rash, itching, swelling of the face or mouth, or difficulty in breathing occur.

Frequently Asked Questions (FAQs)

What is cefpodoxime syrup used for?

• Cefpodoxime syrup is used to treat bacterial infections of the respiratory tract, ears, throat, urinary tract, and skin, especially in children.

How should cefpodoxime dry syrup be given to children?

• It should be given after proper reconstitution, preferably with food, and strictly according to the dosage advised by the pediatrician.

Is SPINXO Dry Syrup safe for pediatric use?

• Yes, when prescribed appropriately. SPINXO Dry Syrup is manufactured by Green Cross Remedies under stringent quality standards to ensure safety and efficacy.

Who manufactures SPINXO Dry Syrup?

• SPINXO Dry Syrup is manufactured by Green Cross Remedies, a trusted pharmaceutical company in India.

SPINXO Dry Syrup by Green Cross Remedies is a reliable cefpodoxime syrup formulation from a trusted pediatric antibiotic manufacturer in India. Manufactured in a WHO-GMP certified facility, it ensures consistent quality, proven antibacterial efficacy, and dependable therapeutic outcomes, making it a preferred choice for healthcare professionals in managing pediatric bacterial infections.

Disclaimer:

This information is intended for the use of Registered Medical Practitioners, Hospitals, Medical Stores, Pharma Agencies, Healthcare Professionals, Pharmaceutical Company Field Staff, and Pharmacies Only.

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