Cefuroxime Axetil 500 mg Tablet - Product Description

• Cefuroxime axetil 500 mg tablet is a widely prescribed second-generation cephalosporin antibiotic used to treat a broad range of bacterial infections
• Known for its strong bactericidal action and good tolerability, this medicine is commonly recommended by healthcare professionals for respiratory, urinary tract, skin, and soft tissue infections.
• Staxcef 500 Tablet offers dependable clinical performance backed by stringent manufacturing standards.

Composition

Each film-coated tablet contains:

• Cefuroxime Axetil 500 mg

Uses of Cefuroxime Axetil 500 mg Tablet

Cefuroxime axetil tablets are primarily used to manage infections caused by susceptible gram-positive and gram-negative bacteria. The medication is effective against pathogens that commonly cause community-acquired and hospital-associated infections.

Cefuroxime axetil tablet uses include:

• Upper and lower respiratory tract infections
• Acute bacterial sinusitis
• Bronchitis and pneumonia
• Urinary tract infections (UTIs)
• Skin and soft tissue infections
• Ear, nose, and throat (ENT) infections
• Bone and joint infections.
• Gonorrhea (a sexually transmitted infection).
• Meningitis (in some cases, based on physician recommendation).

Indications

STAXCEF 500 Tablet is indicated for infections caused by cefuroxime-sensitive organisms, including:

• Streptococcus pneumoniae
• Haemophilus influenzae
• Escherichia coli
• Klebsiella species
• Staphylococcus aureus (non-MRSA)

The formulation is suitable for adult patients and adolescents, as advised by a physician.

Mechanism of Action

• Cefuroxime axetil is a prodrug that converts into its active form, cefuroxime, after oral administration.
• It works by inhibiting bacterial cell wall synthesis. By binding to penicillin-binding proteins (PBPs), the drug disrupts the structural integrity of the bacterial cell wall, leading to cell lysis and death.
• This bactericidal mechanism makes cefuroxime axetil tablets 500 mg highly effective against actively dividing bacteria.
• It has a broad spectrum of activity against both Gram-positive and Gram-negative bacteria.

Dosage and Administration

The cefuroxime axetil 500 mg tablet dosage depends on the severity of infection, patient age, renal function, and clinical response.

General dosage guidelines:

• Adults: 250 mg to 500 mg twice daily
• Severe infections: 500 mg twice daily

STAXCEF 500 Tablet should be taken after food to improve absorption. Always complete the full prescribed course, even if symptoms improve early.

Side Effects of Cefuroxime Axetil 500 mg Tablet

Like all antibiotics, cefuroxime axetil 500 mg tablet may cause mild to moderate side effects in some individuals.

Common side effects include:

• Nausea or vomiting
• Diarrhea
• Abdominal discomfort
• Headache

Rare but serious effects:

• Allergic reactions (rash, itching, swelling)
• Severe diarrhea due to antibiotic-associated colitis

Most side effects are temporary and resolve without intervention. Patients should seek medical advice if symptoms persist or worsen.

Contraindications

Cefuroxime axetil tablets should not be used in patients with:

• Known hypersensitivity to cefuroxime or other cephalosporins
• History of severe allergic reactions to beta-lactam antibiotics

Caution is advised in patients with renal impairment or gastrointestinal disorders.

Drug Interactions

Cefuroxime 500 mg tablet may interact with:

• Antacids (may reduce absorption)
• Probenecid (increases serum concentration of cefuroxime)
• Oral anticoagulants (may alter INR levels)

Patients should inform their healthcare provider about all medications they are currently taking.

Storage Instructions

• Store below 25°C
• Protect from moisture and direct sunlight
• Keep out of reach of children

Do not use the tablet after the expiry date printed on the pack.

Cefuroxime Axetil 500 mg Tablet price-STAXCEF 500 Tablet (MRP) :299.00

Expert Advice

• To achieve optimal therapeutic outcomes with cefuroxime axetil 500 mg tablet, patients should strictly follow the prescribed dosage schedule and avoid skipping doses.
• Antibiotics should never be self-medicated or shared.
• Adequate hydration and timely reporting of adverse effects help ensure safe and effective treatment.
• Take it with food to avoid an upset stomach.
• Discontinue Cefuroxime and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
• Avoid consuming alcohol while taking Cefuroxime as it may cause increased side effects.

Frequently Asked Questions (FAQs)-Cefuroxime Axetil Tablets 500 mg

Can cefuroxime axetil 500 mg tablet be taken on an empty stomach?

• It is recommended to take the tablet after meals to enhance absorption and reduce gastric discomfort.

Can I stop taking cefuroxime once I feel better?

• No. Completing the full prescribed course is essential to prevent antibiotic resistance.

Is cefuroxime effective for viral infections?

• No. Cefuroxime axetil tablets are effective only against bacterial infections and should not be used for viral illnesses like the common cold or flu.

Is cefuroxime safe during pregnancy?

• Cefuroxime is generally considered safe during pregnancy when prescribed by a healthcare professional.

Cefuroxime axetil 500 mg tablet, marketed as STAXCEF 500 Tablet, is a high-quality antibiotic formulation manufactured by Green Cross Remedies, a trusted name in the Indian pharmaceutical industry. Each tablet contains Cefuroxime Axetil 500 mg and is produced in WHO-GMP certified facilities, ensuring consistent quality, safety, and efficacy. 

Disclaimer:

This information is intended for the use of Registered Medical Practitioners, Hospitals, Medical Stores, Pharma Agencies, Healthcare Professionals, Pharmaceutical Company Field Staff, and Pharmacies Only.

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