DIARE M1 Tablet

Glimepiride 1 mg, Metformin (ER) 500 mg Tablet 

DIARE M1 Tablet - A Powerful Combination for Diabetes Management

Composition:

Each uncoated tablet contains:

• Metformin hydrochloride IP 500 mg (sustained release form)
• Glimepiride IP 1 mg

Key Feature:

• Higher Bio-Availability: Matches International Standards
• Longer Duration of Action –Better Tolerability
• Choice of Two Strengths Ensures
• Dosage Flexibility
• Effective Hypo Glycemic Control
• Reduced Risk of Hypoglycemia

Uses and Indications:

DIARE M1 Tablet is indicated for the management of Type 2 diabetes mellitus, particularly in patients who require dual therapy to achieve better glycemic control.

1. Management of Type 2 Diabetes Mellitus:

• Helps lower blood glucose levels in adults with Type 2 diabetes.
• Suitable for patients who are unable to achieve adequate control with Metformin or Glimepiride alone.

2. Improvement of Glycemic Control:

• The combination works synergistically to improve overall blood sugar control.
• Metformin reduces hepatic glucose production and increases insulin sensitivity, while Glimepiride stimulates pancreatic insulin secretion.

3. Weight Management:

• Metformin is associated with weight neutrality or modest weight loss, making it suitable for overweight patients with diabetes.

4. Reduction of Cardiovascular Risk:

• Studies suggest that effective management of diabetes with this combination may reduce the risk of cardiovascular complications associated with diabetes.

5. Prevention of Diabetes-Related Complications:

• Aims to prevent or delay the onset of complications associated with long-term uncontrolled diabetes, such as neuropathy, nephropathy, and retinopathy.

Dosage:

• Recommended Dosage: Usually, 1 tablet once daily, or as prescribed by your healthcare provider.
• Administration: Take with food to minimize gastrointestinal discomfort.

Mechanism of Action:

DIARE M1 Tablet combines the effects of Metformin and Glimepiride:

• Metformin: Works primarily by reducing glucose production in the liver and improving insulin sensitivity, leading to better glucose uptake in the muscles.
• Glimepiride: Stimulates the pancreas to release more insulin, thereby lowering blood sugar levels effectively.

Side Effects:

Common side effects may include:

• Gastrointestinal disturbances (nausea, diarrhea)
• Hypoglycemia (low blood sugar)
• Allergic reactions (rare)

Consult a healthcare professional if side effects persist or worsen.

Contraindications:

DIARE M1 Tablet should not be used in patients with:

• Severe renal impairment
• Diabetic ketoacidosis
• Known hypersensitivity to Metformin or Glimepiride

Drug Interactions:

DIARE M1 Tablet may interact with:

• Other anti diabetic medications
• Certain diuretics
• Corticosteroids

For the Use of Registered Medical Practitioners, Hospitals, Pharmaceutical Company Field Staff and Pharmacies Only.

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