Glimepiride 2 mg, Metformin (ER) 500 mg Tablet
DIARE M2 Tablet - A Powerful Combination for Diabetes Management
Composition:
Each uncoated tablet contains:
- Metformin hydrochloride IP 500 mg (sustained release form)
- Glimepiride IP 2 mg
Key Feature:
- Higher Bio-Availability: Matches International Standards
- Longer Duration of Action –Better Tolerability
- Choice of Two Strengths Ensures
- Dosage Flexibility
- Effective Hypo Glycemic Control
- Reduced Risk of Hypoglycemia
Uses and Indications:
DIARE M2 Tablet is indicated for the management of Type 2 diabetes mellitus, particularly in patients who require dual therapy to achieve better glycemic control.
1.Management of Type 2 Diabetes Mellitus:
- Helps lower blood glucose levels in adults with Type 2 diabetes.
- Suitable for patients who are unable to achieve adequate control with Metformin or Glimepiride alone.
2.Improvement of Glycemic Control:
- The combination works synergistically to improve overall blood sugar control.
- Metformin reduces hepatic glucose production and increases insulin sensitivity, while Glimepiride stimulates pancreatic insulin secretion.
3.Weight Management:
- Metformin is associated with weight neutrality or modest weight loss, making it suitable for overweight patients with diabetes.
4.Reduction of Cardiovascular Risk:
- Studies suggest that effective management of diabetes with this combination may reduce the risk of cardiovascular complications associated with diabetes.
5.Prevention of Diabetes-Related Complications:
- Aims to prevent or delay the onset of complications associated with long-term uncontrolled diabetes, such as neuropathy, nephropathy, and retinopathy.
Dosage:
- Recommended Dosage: Usually, 1 tablet once daily, or as prescribed by your healthcare provider.
- Administration: Take with food to minimize gastrointestinal discomfort.
Mechanism of Action:
DIARE M2 Tablet combines the effects of Metformin and Glimepiride:
- Metformin: Works primarily by reducing glucose production in the liver and improving insulin sensitivity, leading to better glucose uptake in the muscles.
- Glimepiride: Stimulates the pancreas to release more insulin, thereby lowering blood sugar levels effectively.
Side Effects:
Common side effects may include:
- Gastrointestinal disturbances (nausea, diarrhea)
- Hypoglycemia (low blood sugar)
- Allergic reactions (rare)
Consult a healthcare professional if side effects persist or worsen.
Contraindications:
DIARE M2 Tablet should not be used in patients with:
- Severe renal impairment
- Diabetic ketoacidosis
- Known hypersensitivity to Metformin or Glimepiride
Drug Interactions:
DIARE M2 Tablet may interact with:
- Other anti diabetic medications
- Certain diuretics
- Corticosteroids
For the Use of Registered Medical Practitioners, Hospitals, Pharmaceutical Company Field Staff and Pharmacies Only.
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