ELYCTIN 12 TABLET
Ivermectin USP 12 mg
MECHANISM OF ACTION OF IVERMECTIN 12MG (ELYCTIN 12 TABLET):
IVERMECTIN SELECTIVELY BINDS AND WITH HIGH AFFINITY TO GLUTAMATE-GATED CHLORIDE ION CHANNELS, WHICH OCCUR IN INVERTEBRATE NERVE AND MUSCLE CELLS LEADING TO AN INCREASE IN THE PERMEABILITY OF CELL MEMBRANES TO CHLORIDE IONS WITH HYPERPOLARIZATION OF THE NERVE OR MUSCLE CELL AND, ULTIMATELY, DEATH OF THE PARASITE. ABSORPTION: ABSORBED FROM THE GI TRACT (ORAL); PEAK PLASMA CONCENTRATIONS AFTER 4 HR. DISTRIBUTION: ENTERS BREAST MILK (<2%). PROTEIN-BINDING: ABOUT 93%. EXCRETION: VIA FAECES (AS METABOLITES), VIA URINE (<1%). PLASMA ELIMINATION HALF-LIFE: 12 HR.
DRUG INTERACTIONS OF IVERMECTIN 12MG (ELYCTIN 12 TABLET):
BIOAVAILABILITY MAY BE INCREASED BY ALCOHOL, LEVAMISOLE.
SIDE EFFECTS OF IVERMECTIN 12MG (ELYCTIN 12 TABLET):
DIARRHOEA, NAUSEA, VOMITING, DIZZINESS, PRURITUS, URTICARIA, RASH, ARTHRALGIA, FEVER, MYALGIA, ASTHENIA, POSTURAL HYPOTENSION, TACHYCARDIA, OEDEMA, LYMPHADENOPATHY, SORE THROAT, COUGH, HEADACHE, SOMNOLENCE, TRANSIENT EOSINOPHILIA, RAISED LIVER ENZYME VALUES.
Ivermectin Uses
For Use of registered medical practitioner or a hospital only
