Nitrofurantoin IP 100 mg – NETROET 100 SR Tablet

NETROET 100 SR Tablet contains Nitrofurantoin IP 100 mg in a film-coated sustained-release formulation. It is an antibiotic prescribed by healthcare professionals for certain bacterial urinary tract infections (UTIs), particularly uncomplicated lower urinary tract infections such as bladder infections. The sustained-release formulation is designed to release the medicine over an extended period, according to its approved formulation characteristics.

Composition of NETROET 100 SR Tablet

Each film-coated sustained-release tablet contains:

• Nitrofurantoin IP – 100 mg
• Excipients – q.s.

Nitrofurantoin 100 mg Sustained Release Tablet Uses

Nitrofurantoin is an antibacterial medicine that acts against susceptible bacteria responsible for certain urinary tract infections. Doctors may prescribe it for:

• Uncomplicated lower urinary tract infections.
• Acute bacterial cystitis, or bladder infection.
• Certain bacterial urine infections caused by susceptible organisms.
• Urinary symptoms associated with a confirmed or clinically diagnosed susceptible bacterial infection.

The medicine is not appropriate for every urine infection. It does not reliably treat kidney infections or infections that have spread beyond the urinary tract. A healthcare professional should determine whether Nitrofurantoin is suitable for the individual patient.

Useful in:

1. Treatment of Urinary Tract Infections (UTIs): Nitrofurantoin is primarily used to treat infections caused by susceptible strains of bacteria in the urinary tract, including cystitis and pyelonephritis.
2. Prophylaxis against Recurrent UTIs: It may be prescribed to prevent recurrent urinary tract infections in individuals with a history of frequent UTIs.

Indications of Nitrofurantoin IP 100 mg SR Tablet

NETROET 100 SR Tablet may be prescribed for eligible patients with bacterial lower urinary tract infections when the causative organism is susceptible to Nitrofurantoin. Urine culture and antibiotic-susceptibility testing may be recommended, particularly in recurrent, complicated, or treatment-resistant infections.

Burning during urination, frequent urination, urgency, and lower abdominal discomfort can occur with cystitis. However, these symptoms may have other causes and do not independently confirm a bacterial infection.

Indicated in:

• Acute Uncomplicated Cystitis: Indicated for the treatment of uncomplicated bladder infections in women.
• Chronic Urinary Tract Infections: Suitable for patients who experience chronic UTIs to minimize recurrence.
• Surgical Prophylaxis: May be used before urinary tract surgeries to prevent infection.
• Pregnancy-Related UTIs: Nitrofurantoin can be used cautiously in pregnant women for UTI treatment, particularly in the second and third trimesters, as advised by a healthcare professional.

Nitrofurantoin is a urinary antibacterial agent. Inside susceptible bacterial cells, it is converted into reactive intermediates that damage multiple bacterial components, including proteins, ribosomal functions, and genetic material. This multi-target action interferes with essential bacterial processes and helps control susceptible bacteria in the urinary tract.

Nitrofurantoin 100 mg Tablet Dosage

The dosage and duration of treatment must be determined by a qualified healthcare professional based on the diagnosis, formulation, kidney function, and patient-specific factors.

• Take the tablet exactly as prescribed.
• Follow the product-specific instructions regarding administration with food.
• Swallow the tablet as directed; do not crush or alter a sustained-release tablet unless the product instructions specifically permit it.
• Complete the prescribed course unless your healthcare professional advises otherwise.
• If a dose is missed, follow the patient leaflet or ask a pharmacist. Do not double the next dose.

Do not self-medicate with antibiotics or use leftover tablets for a new infection.

Nitrofurantoin 100 mg Tablet Side Effects

Possible adverse effects include nausea, vomiting, reduced appetite, abdominal discomfort, and diarrhoea. Nitrofurantoin may also cause headache or dizziness. Urine can become darker yellow or brown during treatment; this may be harmless, but unexplained or persistent changes should be discussed with a healthcare professional.

Rare but serious reactions can include lung injury, liver injury, nerve damage, and severe allergic reactions. Seek urgent medical attention for difficulty breathing, facial or throat swelling, severe rash, or other serious symptoms. Report persistent cough, chest pain, jaundice, numbness, or tingling promptly.

Contraindications and Precautions

Nitrofurantoin may be unsuitable for people with significant renal impairment, a previous serious reaction to the medicine, or certain conditions affecting red blood cells. It is generally avoided in patients with a history of Nitrofurantoin-associated liver dysfunction and in certain stages of pregnancy, particularly near delivery, because of the risk of haemolysis in the newborn.

People with glucose-6-phosphate dehydrogenase (G6PD) deficiency may have an increased risk of haemolytic anaemia. Older adults and patients with kidney or liver problems require careful clinical assessment.

Nitrofurantoin is not a substitute for appropriate treatment of suspected kidney infection. Fever, chills, flank or back pain, vomiting, or worsening symptoms require prompt medical evaluation.

Drug Interactions

Inform your doctor about all medicines and supplements you use. Magnesium trisilicate-containing antacids may reduce Nitrofurantoin absorption. Probenecid and sulfinpyrazone can affect its renal excretion and may increase toxicity or reduce urinary concentrations. Some medicines used to treat urinary symptoms may also affect its antibacterial activity. Your healthcare professional or pharmacist can assess the relevance of these interactions to your treatment.

Storage Instructions

Store NETROET 100 SR Tablet according to the instructions on its packaging, away from excessive heat, moisture, and direct sunlight. Keep it in its original packaging and out of the reach of children. Do not use tablets beyond their expiry date, and do not use damaged or improperly stored medicine.

Nitrofurantoin 100 mg Tablet Price

NETROET 100 SR Tablet MRP: 87.00 for 10 Tablets

Expert Advice

• Nitrofurantoin should be taken only on the advice of a qualified healthcare professional.
• Follow the prescribed dose and duration, take the medicine according to the product instructions, and do not share antibiotics with others. Tell your doctor about kidney disease, liver problems, G6PD deficiency, pregnancy, breastfeeding, allergies, and all medicines you take. Maintain normal hydration unless you have been advised to restrict fluids.
• Seek prompt medical advice if symptoms worsen, fail to improve within the period specified by your clinician, or are accompanied by fever, chills, or back pain.
• Stop and seek urgent help if you experience signs of a serious allergic reaction or breathing difficulty.
• Appropriate antibiotic use helps reduce the risk of antimicrobial resistance.

Frequently Asked Questions (FAQs)

1. What is Nitrofurantoin 100 mg SR tablet used for?

• Nitrofurantoin is prescribed for certain susceptible bacterial lower urinary tract infections, particularly uncomplicated bladder infections. It is not suitable for every type of UTI.

2. Is Nitrofurantoin 100 mg used for UTI?

• Yes. Healthcare professionals may prescribe Nitrofurantoin for eligible patients with susceptible bacterial UTIs affecting the lower urinary tract.

3. Can Nitrofurantoin help with burning urination?

• It may help when burning urination is caused by a susceptible bacterial UTI. Other causes require different evaluation and treatment.

4. What are the side effects of Nitrofurantoin 100 mg?

• Common side effects include nausea, vomiting, diarrhoea, abdominal discomfort, and headache. Serious lung, liver, nerve, or allergic reactions are uncommon but require prompt medical attention.

5. How should Nitrofurantoin SR tablets be taken?

• Take the prescribed formulation exactly as directed. Follow the packaging instructions for administration and do not crush or alter a sustained-release tablet unless specifically permitted.

6. Can Nitrofurantoin 100 mg be taken during pregnancy?

• Use during pregnancy requires medical assessment. Nitrofurantoin is generally avoided near delivery and may be unsuitable in certain circumstances. Consult your obstetrician before taking it.

7. Does Nitrofurantoin cause dark-coloured urine?

• Yes. Nitrofurantoin can cause dark yellow or brown urine. Seek medical advice if the change is accompanied by jaundice, severe discomfort, or other concerning symptoms.

8. What are the uses of Nitrofurantoin tablets in Hindi?

• Nitrofurantoin टैबलेट का उपयोग डॉक्टर की सलाह पर कुछ बैक्टीरियल यूरिनरी ट्रैक्ट इन्फेक्शन (UTI), विशेषकर मूत्राशय के संक्रमण, के इलाज में किया जाता है। इसका उपयोग संक्रमण के प्रकार और मरीज की स्थिति के अनुसार होना चाहिए।

9. What is the price of Nitrofurantoin 100 mg SR tablet in India?

• The price varies according to the brand, pack size, and printed MRP. Check the packaging or ask an authorised pharmacy for the current price.

10. Who manufactures NETROET 100 SR Tablet?

• NETROET 100 SR Tablet is the Nitrofurantoin IP 100 mg sustained-release product identified for Green Cross Remedies.

NETROET 100 SR Tablet contains Nitrofurantoin IP 100 mg in a film-coated sustained-release formulation and is intended for prescription-led treatment of eligible bacterial lower urinary tract infections manufactured by Green Cross Remedies.

Disclaimer:

This information is intended for the use of Registered Medical Practitioners, Hospitals, Medical Stores, Pharma Agencies, Healthcare Professionals, Pharmaceutical Company Field Staff, and Pharmacies Only.

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