ROZUSTEEN -20 Tablet


ROZUSTEEN -20 Tablet


ROSUVASTATIN 20 MG TABLETS



ROZUSTEEN -20 Tablet

ROZUSTEEN -20 Tablet

COMPOSITION:

Each film coated tablet contains:

Rosuvastatin Calcium ip eq to Rosuvastatin 20 mg

 

 

Rosuvastatin

It is a selective and competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme that converts 3-hydroxy-3-methylglutaryl coenzyme A to mevalonate, a precursor for cholesterol. The primary site of action of rosuvastatin is the liver, the target organ for cholesterol lowering. Rosuvastatin increases the number of hepatic LDL receptors on the cell-surface, enhancing uptake and catabolism of LDL and it inhibits the hepatic synthesis of VLDL, thereby reducing the total number of VLDL and LDL particles.

Indications -Use of Rosuvastatin 20 Tablet (ROZUSTEEN -20 Tablet):

Primary hypercholesterolaemia (type IIa including heterozygous familial hypercholesterolaemia) or mixed dyslipidaemia (type IIb), including familial hypercolesterolaemia.

Dosage of Rosuvastatin 20 Tablet(ROZUSTEEN -20 Tablet):

The recommended starting dose is 10 mg orally once daily. A dose adjustment to 20mg can be made after 4 weeks .

Contra-Indications of Rosuvastatin 20 Tablet(ROZUSTEEN -20 Tablet):

Severe renal impairment, active liver disease, hypersensitivity to rosuvastatin, myopathy, cyclosporin, pregnancy and lactation .

Side Effects of Rosuvastatin 20 Tablet (ROZUSTEEN -20 Tablet):

Headache, dizziness, constipation, nausea, abdominal pain, myalgia and asthenia.

Drug Interactions of Rosuvastatin 20 Tablet (ROZUSTEEN -20 Tablet):

Cyclosporin, warfarin, gemfibrozil, erythromycin, antacids, oral contraceptive/hormone replacement therapy (HRT).

 

For Use of registered medical practitioner or a hospital only

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