WEQGLO Cream
Hyroquinone USP 2 %, Tretinoin USP 0.025 %, Mometasone 0.1% Use, Indication, Side Effects, Dosage, Mechanism of Action, Price, Contra-Indications, Drug Interactions....
WEQGLO Cream
Uses and Indications:
WEQGLO Cream is typically used for:
- Hyperpigmentation Disorders: It is often used for the treatment of skin conditions such as melasma, post-inflammatory hyperpigmentation, age spots, and freckles.
- Skin Lightening: Hydroquinone is a skin-lightening agent that reduces the appearance of dark spots and uneven skin tone.
- Anti-aging and Skin Renewal: Tretinoin (a form of Vitamin A) promotes skin cell turnover, reducing wrinkles, fine lines, and improving skin texture.
- Inflammation and Allergies: Mometasone is a corticosteroid that reduces inflammation and itching, which helps in cases of inflammatory skin conditions.
Mechanism of Action:
- Hydroquinone (2%): Hydroquinone works by inhibiting the enzyme tyrosinase, which is involved in the production of melanin (skin pigment). This leads to the lightening of hyperpigmented areas.
- Tretinoin (0.025%): Tretinoin promotes the turnover of skin cells by increasing the rate at which cells are shed from the skin's surface, which helps to improve skin texture and reduce the appearance of wrinkles and dark spots.
- Mometasone (0.1%): Mometasone is a potent corticosteroid that reduces inflammation by suppressing the immune response. It also helps to alleviate itching and redness associated with skin conditions like eczema, dermatitis, and allergic reactions.
Dosage:
- Adults and children over 12 years: Apply a thin layer of WEQGLO cream once daily to the affected area(s) in the evening (before bedtime), after cleansing the skin.
- Duration of use: Typically, the cream is used for 4 to 6 weeks, depending on the severity of the skin condition, but prolonged use should be avoided to reduce the risk of side effects.
Side Effects:
Common side effects may include:
- Skin Irritation: Redness, peeling, burning, stinging, or dryness at the site of application.
- Thinning of Skin: Prolonged use of corticosteroids (like mometasone) can lead to thinning of the skin.
- Increased Sensitivity to Sunlight: Hydroquinone and tretinoin can make the skin more sensitive to sunlight, so patients should use sunscreen during the day.
- Allergic Reactions: Rarely, an allergic reaction may occur, causing symptoms like swelling, rash, or itching.
- Hyperpigmentation: In rare cases, excessive use of hydroquinone may lead to ochronosis (a condition where the skin turns blue-black).
Contraindications:
- Allergy to any of the ingredients: Patients who have hypersensitivity to hydroquinone, tretinoin, or mometasone should avoid using WEQGLO cream.
- Pregnancy: Tretinoin is classified as a Category C drug for pregnancy. It should be avoided during pregnancy, especially during the first trimester, unless the benefits outweigh the risks.
- Breastfeeding: Caution is required when using this cream while breastfeeding as both hydroquinone and tretinoin can pass into breast milk.
- Active skin conditions: It should not be used on broken or inflamed skin, including open wounds or sunburned skin.
Drug Interactions:
- Topical Medications: Combining WEQGLO cream with other topical products that irritate the skin, such as other retinoids or abrasive skin treatments, may cause excessive dryness or irritation.
- Systemic Steroids: Since mometasone is a corticosteroid, combining it with systemic steroids or other immunosuppressants may increase the risk of systemic absorption and side effects like immune suppression.
- Photosensitizing Agents: Drugs that increase the skin’s sensitivity to sunlight, like certain antibiotics (e.g., tetracyclines), may increase the risk of sunburn when used alongside WEQGLO.
For Use of registered medical practitioner or a hospital only