Cefpodoxime Clavulanic Acid Dry Syrup - SPINXO CLAV Dry Syrup

• Cefpodoxime clavulanic acid dry syrup is a broad-spectrum pediatric antibiotic formulation widely prescribed for the effective treatment of bacterial infections in infants and children.
• This advanced combination pairs a third-generation cephalosporin with a beta-lactamase inhibitor, ensuring enhanced antibacterial coverage and reduced resistance risk.
• SPINXO CLAV Dry Syrup is designed for reliable oral administration in children, offering accurate dosing, improved palatability, and consistent therapeutic outcomes when used as directed by a healthcare professional.

Product Composition

Each 5 ml of reconstituted SPINXO CLAV Dry Syrup contains:

• Cefpodoxime Proxetil IP – 50 mg
• Clavulanic Acid IP – 31.25 mg
•  Flavoured base q.s.
•  Supplied with sterile water for reconstitution

Key Ingredients:

• Cefpodoxime: A broad-spectrum cephalosporin antibiotic effective against various bacterial infections.
• Clavulanic Acid: A beta-lactamase inhibitor that prevents bacteria from breaking down Cefpodoxime, enhancing its effectiveness.

Uses and Indications

Cefpodoxime proxetil clavulanate syrup uses include treatment of various pediatric bacterial infections such as:

• Upper and lower respiratory tract infections
• Acute otitis media
• Tonsillitis and pharyngitis
• Acute bacterial sinusitis
• Urinary tract infections (UTIs)
• Skin and soft tissue infections
• Excellent Coverage Against Gram +Ve And Gram –Ve Pathogens
• Ear infections (otitis media)
• Kills Even ESBL Producing Pathogens
• Sinusitis
• Gastro Intestinal Tract Infection
• Cervicitis Meningitis

This formulation is commonly prescribed when resistance to single-agent antibiotics is suspected.

Mechanism of Action

• Cefpodoxime proxetil is a prodrug that converts into its active form, cefpodoxime, after oral administration. It inhibits bacterial cell wall synthesis, leading to bacterial cell death. However, certain bacteria produce beta-lactamase enzymes that can reduce antibiotic effectiveness.
• Clavulanic acid neutralizes these enzymes, protecting cefpodoxime from degradation. This synergistic action makes cefpodoxime and potassium clavulanate syrup highly effective against resistant bacterial strains, ensuring broader antimicrobial coverage and sustained clinical response.

Dosage and Administration

Cefpodoxime proxetil clavulanate syrup dosage for children should be strictly determined by a pediatrician based on age, body weight, severity of infection, and clinical response.

General guidelines:

·        Administer twice daily

·        Shake well before each use

·        Measure dose using the provided measuring cup

·        Preferably give after food to reduce gastric discomfort

Do not exceed the prescribed dose or duration.

Side Effects

Most children tolerate the medication well. However, cefpodoxime proxetil clavulanate syrup side effects may include:

• Mild diarrhea
• Nausea or vomiting
• Abdominal discomfort
• Skin rash

Rare but serious allergic reactions may occur. Immediate medical attention is required if swelling of the face, lips, or breathing difficulty is observed.

Contraindications and Precautions

•   Contraindicated in patients with known hypersensitivity to Cephalosporins or Clavulanic acid
•   Use with caution in children with a history of gastrointestinal disorders
• Renal impairment may require dosage adjustment
• Not recommended without medical supervision

Drug Interactions

• Concomitant use with anticoagulants may increase bleeding risk
• Probenecid can increase cefpodoxime levels
• May reduce effectiveness of oral vaccines

Always inform the physician about all medications the child is taking.

Usage Instructions:

• Store the syrup in a cool, dry place, away from direct sunlight.
• After reconstitution (mixing with water), store the syrup in the refrigerator and use within 7 to 14 days, as per the manufacturer’s instructions.
• Reconstitute the dry syrup with sterile water as per the instructions provided. Ensure to shake well before administration. Follow the prescribed dosage and complete the full course of treatment for optimal results.

Storage Instructions

• Store below 25°C
• Protect from moisture and direct sunlight
• After reconstitution, store as directed and use within the prescribed time
• Keep out of reach of children

Cefpodoxime Proxetil + Clavulanic Acid Dry Syrup Price - SPINXO CLAV Dry Syrup (MRP): 126.28

Expert Advice for Cefpodoxime Proxetil & Clavulanic Acid Dry Syrup

• Cefpodoxime clavulanic acid dry syrup should always be administered exactly as prescribed by a qualified healthcare professional.
• Avoid missing doses and do not stop treatment early, even if symptoms improve, as incomplete therapy may lead to recurrence or antibiotic resistance.
• This medication should never be self-medicated or shared between children.
• Ensure adequate hydration during therapy.
• Administer the syrup after meals to minimize stomach upset.
• Discontinue the medicine and seek immediate medical attention if the child develops rash, itching, swelling of the face or mouth, or breathing difficulty.
• Avoid combining antibiotics without medical advice to ensure safe and effective treatment.

Frequently Asked Questions (FAQs)

What is Cefpodoxime proxetil potassium clavulanate syrup used for?

• It is used to treat respiratory, ENT, urinary, and skin infections caused by susceptible bacteria in children.

Is SPINXO CLAV Dry Syrup safe for infants?

• Yes, when prescribed by a pediatrician and administered at the recommended dosage.

Which is the best cefpodoxime proxetil clavulanate dry syrup in India?

• SPINXO CLAV Dry Syrup manufactured by Green Cross Remedies is known for consistent quality and reliable clinical performance.

Who is the manufacturer of SPINXO CLAV Dry Syrup?

• SPINXO CLAV Dry Syrup is manufactured by Green Cross Remedies, a trusted pharmaceutical company in India.

Cefpodoxime clavulanic acid dry syrup, marketed as SPINXO CLAV Dry Syrup, is a well-balanced pediatric antibiotic formulation manufactured by Green Cross Remedies, a reputed Indian pharmaceutical company. Developed to meet modern pediatric infection management needs, SPINXO CLAV Dry Syrup ensures effective bacterial coverage, safety, and ease of administration, making it a dependable choice for pediatricians across India.

SPINXO CLAV Dry Syrup by Green Cross Remedies is a reliable Cefpodoxime Proxetil 50 mg and Clavulanic Acid 31.25 mg dry syrup from a trusted leading manufacturer in India. Manufactured in a WHO-GMP certified facility, it ensures consistent quality, proven efficacy, and dependable therapeutic outcomes, making it a preferred pediatric antibiotic choice for healthcare professionals.

Disclaimer:

This information is intended for the use of Registered Medical Practitioners, Hospitals, Medical Stores, Pharma Agencies, Healthcare Professionals, Pharmaceutical Company Field Staff, and Pharmacies Only.

GREEN CROSS REMEDIES