Cefuroxime Axetil & Potassium Clavulanate Tablets - Product Description

• Cefuroxime axetil & potassium clavulanate tablets are a widely prescribed combination antibiotic used for the effective management of moderate to severe bacterial infections.
• This dual-action formulation brings together a second-generation cephalosporin with a beta-lactamase inhibitor, enhancing antibacterial coverage and helping overcome resistance caused by enzyme-producing bacteria.
• This combination is especially valued in clinical practice for respiratory tract infections, ENT infections, urinary tract infections, and skin and soft tissue infections.
• By combining two complementary agents, it ensures reliable outcomes in infections where single-agent therapy may be insufficient.
• Cefuroxime Axetil, a broad-spectrum cephalosporin antibiotic with Potassium Clavulanic Acid, a beta-lactamase inhibitor. This powerful combination enhances the effectiveness of Cefuroxime against resistant bacterial strains, making it a reliable option for treating various infections.

Composition

• Cefuroxime Axetil IP – 500 mg
• Potassium Clavulanic Acid – 125 mg

Uses of Cefuroxime Axetil & Potassium Clavulanate Tablets

Cefuroxime axetil and potassium clavulanate tablets are prescribed to treat a broad range of bacterial infections caused by susceptible organisms. Common uses include:

• Lower and upper respiratory tract infections
• Acute and chronic sinusitis
• Respiratory tract infections (e.g., pneumonia, bronchitis)
• Urinary tract infections
• Skin and soft tissue infections
• Ear infections (otitis media)
• Dental and postoperative infections

The addition of clavulanate helps restore cefuroxime’s activity against bacteria that produce beta-lactamase enzymes, improving

clinical success rates.

Indications

• Doctors commonly recommend Cefuroxime Clavulanic Acid tablets for patients who do not respond adequately to first-line antibiotics.
• It is indicated in infections caused by gram-positive and gram-negative bacteria, including resistant strains where enzyme-mediated resistance is suspected.

Mechanism of Action

• Cefuroxime works by inhibiting bacterial cell wall synthesis, leading to bacterial cell death.
• Potassium clavulanate, on the other hand, does not possess significant antibacterial activity on its own but plays a crucial supportive role. It inhibits beta-lactamase enzymes produced by resistant bacteria, protecting cefuroxime from degradation.
• Together, this mechanism allows cefuroxime potassium clavulanate tablets to deliver broader and more reliable antibacterial coverage.

Dosage and Administration

The dosage of cefuroxime axetil & potassium clavulanate tablets depends on the type and severity of infection, patient age, and clinical response.

General guidance:

• Usually taken twice daily after meals
• Should be swallowed whole with water
• Duration of therapy typically ranges from 5 to 10 days

Always follow the prescribing physician’s instructions. Do not discontinue the medication prematurely, even if symptoms improve.

Side Effects of Cefuroxime Clavulanic Acid Tablets

Like all antibiotics, this combination may cause some side effects, though not everyone experiences them. Commonly reported Cefuroxime Clavulanic Acid side effects include:

• Nausea or vomiting
• Diarrhea
• Abdominal discomfort
• Headache
• Mild skin rash

Rare but serious reactions may include allergic responses, severe diarrhea, or liver enzyme alterations. Immediate medical attention is advised if unusual symptoms occur.

Contraindications

Cefuroxime & clavulanate tablets should be avoided in patients with:

• Known hypersensitivity to cephalosporins or beta-lactam antibiotics
• History of severe allergic reactions to penicillins
• Severe hepatic dysfunction (use with caution)

A complete medical history should be shared with the healthcare provider before starting therapy.

Drug Interactions

Certain medicines may interact with cefuroxime axetil and potassium clavulanate tablet, affecting efficacy or increasing side effects:

• Oral anticoagulants (may increase bleeding risk)
• Probenecid (may increase cefuroxime levels)
• Oral contraceptives (reduced effectiveness possible)

Patients should inform their doctor about all ongoing medications and supplements.

Storage Instructions

• Store below 25°C
• Protect from moisture and direct sunlight
• Keep out of reach of children
• Do not use after the expiry date printed on the pack

Expert Advice

• Cefuroxime axetil and potassium clavulanate tablets should always be taken as prescribed and completed as a full course to prevent antibiotic resistance.
• Do not skip any doses and finish the full course of treatment even if you feel better.
• Patients with kidney or liver conditions should use this medication under medical supervision.
• Avoid self-medication and consult a healthcare professional for proper diagnosis and dosage adjustment.

Cefuroxime Axetil & Potassium Clavulanate Tablets price - STAXCEF CV 500 Tablet (MRP) - 374.42

Frequently Asked Questions (FAQs) - Cefuroxime Axetil & Potassium Clavulanate Tablets

What is cefuroxime axetil and potassium clavulanate tablets used for?

• They are used to treat bacterial infections of the respiratory tract, ENT, urinary tract, skin, and soft tissues.

Is this medicine effective against resistant bacteria?

• Yes, the clavulanate component helps combat beta-lactamase–producing resistant bacteria.

Can I take this tablet on an empty stomach?

• It is recommended to take it after food to reduce gastric discomfort and improve absorption.

Can these tablets be used for viral infections?

• No. They are effective only against bacterial infections, not viral illnesses like flu or common cold.

STAXCEF CV Tablet by Green Cross Remedies is a reliable cefuroxime axetil & potassium clavulanate formulation from a trusted pharmaceutical manufacturer in India. Manufactured in a WHO-GMP certified facility, it ensures consistent quality, proven efficacy, and dependable therapeutic outcomes, making it a preferred choice for healthcare professionals in managing bacterial infections.

Disclaimer:

This information is intended for the use of Registered Medical Practitioners, Hospitals, Medical Stores, Pharma Agencies, Healthcare Professionals, Pharmaceutical Company Field Staff, and Pharmacies Only.

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