Linezolid 600 Tablet – Product Description

Linezolid 600 tablet are a widely prescribed antibiotic used in the treatment of serious bacterial infections caused by resistant gram-positive organisms. This medicine belongs to the oxazolidinone class of antibiotics and is particularly effective where other antibiotics may fail. Due to its targeted mechanism, it is commonly recommended in hospital as well as outpatient settings under medical supervision.

Linezolid 600 Tablet Uses & Indications: 

Linezolid 600 mg (Linxo 600) is used to treat severe bacterial infections, including:

• Pneumonia (community-acquired or hospital-acquired)
• Skin and Soft Tissue Infections (including diabetic foot infections)
• Vancomycin-resistant Enterococcus faecium (VRE) Infections
• Methicillin-resistant Staphylococcus aureus (MRSA) Infections
• Infections caused by Streptococcus and Staphylococcus species

It is typically employed when other antibiotics are ineffective or when bacteria are resistant to standard treatments.

Mechanism of Action:

Linezolid inhibits bacterial protein synthesis by binding to the bacterial ribosome (specifically the 23S rRNA of the 50S subunit). This prevents the formation of a functional initiation complex necessary for protein synthesis, halting bacterial growth and replication, which leads to bacterial death. Linezolid is primarily a bacteriostatic agent, but can also be bactericidal against certain strains, such as Streptococcus pneumonia.

Dosage: Linezolid 600 mg dose

• Adult Dosage:
• Initial Dose: 600 mg orally, twice a day.
• Duration: Typically ranges from 10 to 14 days, depending on the infection type and clinical response.
• Pediatric Dosage: Varies based on the child’s weight, condition, and doctor's recommendations.
• Renal or Hepatic Impairment: Dosage adjustments may be necessary for patients with severe renal or hepatic impairment.
• Dose Take as by Physician or Medical Practitioner.

Linezolid 600 mg Side Effects: 

Common side effects include:

• Gastrointestinal: Diarrhea, nausea, vomiting, and constipation.
• Hematologic: Low platelet count (thrombocytopenia), low white blood cell count (leukopenia), anemia.
• Neurological: Headaches, dizziness, peripheral nephropathy (numbness or tingling in extremities).
• Liver Effects: Elevated liver enzymes (liver toxicity).
• Skin Reactions: Rash or itching.
• Serotonin Syndrome: Rare but severe when combined with certain antidepressants.

Seek medical attention for persistent side effects or signs of an allergic reaction.

Contraindications: Linezolid is contraindicated in the following situations:

• Hypersensitivity: Known allergy to Linezolid or its ingredients.
• Use with Monoamine Oxidase Inhibitors (MAOIs): Concurrent use is contraindicated due to the risk of hypertensive crisis.
• Severe Renal or Hepatic Impairment: May require dosage adjustments or could be contraindicated.
• Pheochromocytoma: Linezolid can increase blood pressure.

Drug Interactions: Linezolid 600 mg Tablet Potential interactions include:

• Serotonergic Drugs: Combining with SSRIs, SNRIs, or other serotonergic drugs may lead to serotonin syndrome.
• Adrenergic Drugs: Co-administration may increase blood pressure.
• Antibiotics: Certain antibiotics like rifampin can interfere with Linezolid's effectiveness.
• Anti-platelet or Anticoagulants: Increased bleeding risk due to thrombocytopenia.
• Anesthetics: Caution is advised when used with certain anesthetics, such as halothane.

Consult with a healthcare provider or pharmacist before starting or combining Linezolid with any other medications to avoid serious interactions.

Storage Instructions: Store linezolide 600 tablets in a cool, dry place away from direct sunlight. Keep out of reach of children. Do not use the tablets after the expiry date mentioned on the pack.

linezolid 600 mg price : Linxo 600 - 372.19/ 10 Tab

Expert advice for Linezolid

• Linezolid treats serious infections caused by certain types of bacteria.
• Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder to treat.
• Avoid taking excessive cheese, processed meats, alcohol, or soy sauce while taking this medication as these may cause an excessive rise in your blood pressure.
• Take it with food to avoid an upset stomach.
• Do not take it for more than 14 days without consulting your doctor.
• Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.

Frequently Asked Questions (FAQ) – Linezolid Tablets

What is Linezolid used for?

• Linezolid is an antibiotic used to treat serious bacterial infections, especially those caused by resistant bacteria such as MRSA (Methicillin-Resistant Staphylococcus aureus), VRE (Vancomycin-Resistant Enterococcus) It is commonly prescribed for pneumonia, skin infections, and certain bloodstream infections.

How should I take Linezolid tablets?

• Usually taken every 12 hours, Swallow the tablet whole with water, Can be taken with or without food, Do not skip doses and complete the full course, Take exactly as prescribed by your doctor.

How long is Linezolid treatment?

• Treatment duration is usually 10 to 14 days, but it may be longer depending on the infection and your condition. Follow your doctor’s instructions.

What are the common side effects of Linezolide 600mg ?

• Diarrhea, Nausea or vomiting, Headache, Dizziness, Taste changes

What are serious side effects to watch for?

• Vision problems (blurred vision, changes in color vision), Unusual bruising or bleeding, Persistent diarrhea, Numbness or tingling in hands or feet, Signs of low blood counts (fatigue, pale skin, frequent infections)

Are there any foods I should avoid?

• Aged cheeses, Smoked or cured meats, Soy sauce, Fermented foods, Alcohol (especially beer and wine)

Is Linezolid safe during pregnancy or breastfeeding?

• Linezolid should only be used during pregnancy or breastfeeding if clearly needed. Always consult your doctor before use.

What should I do if I miss a dose?

• Take it as soon as you remember, If it’s almost time for the next dose, skip the missed dose, Do not double the dose.

LINXO 600 by GREEN CROSS REMEDIES is a reliable Linezolid formulation from a trusted leading Linezolid 600 mg tablet manufacturer in India. Manufactured in a WHO-GMP certified facility, it ensures consistent quality, proven efficacy, and dependable therapeutic outcomes, making it a preferred choice for healthcare professionals in managing serious infections.

Disclaimer:This information is intended for the use of Registered Medical Practitioners, Hospitals, Pharmaceutical Company Field Staff, and Pharmacies Only.