CLOPS ES Tablet
Clonazepam & Escitalopram Tablet Use, Drug Interactions, Side Effects, Special Precautions, Dosage, Price...
CLOPS ES Tablet
Escitalopram 10 mg, Clonazepam 0.5 mg Tablet (FC)
Escitalopram and Clonazepam Tablet (CLOPS ES) Uses :
Escitalopram is used to treat depression and anxiety. It works by helping to restore the balance of a certain natural substance (serotonin) in the brain. Escitalopram belongs to a class of drugs known as selective serotonin reuptake inhibitors (SSRI). It may improve your energy level and feelings of well-being and decrease nervousness.
Clonazepam is used to prevent and control seizures. This medication is known as an anticonvulsant or antiepileptic drug. It is also used to treat panic attacks. Clonazepam works by calming your brain and nerves. It belongs to a class of drugs called benzodiazepines.
Side Effects of Escitalopram 10mg and Clonazepam 0.5mg Tablet (Clops Es):
Nausea, Diarrhoea, Increased Sweating, Insomnia, Impotence, Ejaculation Disorder, Fatigue, Somnolence; Postural Hypotension, Sinusitis, Taste Disturbances. Increased Appetite And Wt Gain.
Drug Interactions of Escitalopram 10mg and Clonazepam 0.5mg Tablet (Clops Es):
Increased Risk Of Bleeding When Used With Aspirin, Nsaids Or Drugs That Affect Coagulation. Serum Levels May Be Reduced By Cyp2c19 Inducers (E.G. Carbamazepine, Rifampin, Phenytoin) Or Cyp3a4 Inducers (E.G. Nafcillin, Nevirapine). Serum Levels May Also Be Increased By Cyp2c19 Inhibitors (E.G. Fluconazole, Fluvoxamine, Omeprazole) Or Cyp3a4 Inhibitors (E.G. Azole Antifungals, Clarithromycin). May Increase Serum Levels Of Desipramine Or Metoprolol. Increased Risk Of Serotonin Syndrome When Used With Linezolid Or Sibutramine. Escitalopram May Enhance The Sedative Effects Of Alcohol. Potentially Fatal: Concomitant Administration With Maois May Lead To Serious Or Fatal Reactions; Should Not Be Started Until At Least 2 Wk After Stopping Escitalopram Or Vice Versa. Moclobemide May Increase The Risk Of Serotonin Syndrome.
Contraindications of Escitalopram 10mg and Clonazepam 0.5mg Tablet (Clops Es):
Concomitant Use With Or Within 2 Wk Of Maoi Withdrawal.
Mechanism Of Action of Escitalopram 10mg and Clonazepam 0.5mg Tablet (Clops Es):
Escitalopram Selectively Inhibits Cns Neuronal Re-Uptake Of Serotonin (5-Ht) And Potentiates Serotonergic Activity. It Has Minimal Effects On Norepinephrine And Dopamine Neuronal Re-Uptake. Onset: 1-2 Wk. Absorption: Readily Absorbed From The Gi Tract (Oral). Distribution: Protein-Binding: 56%. Metabolism: Hepatic; Converted To Metabolites. Excretion: Urine (As Unchanged Drug); 27-32 Hr (Elimination Half-Life).
Special Precautions for Escitalopram 10mg and Clonazepam 0.5mg Tablet (Clops Es):
History Of Mania Or Seizure Disorders; Work Requiring Mental Alertness; Renal And Hepatic Impairment; Pregnancy, Lactation; Withdraw Gradually. Children And Adolescents <18 Yr
For Use of Registered Medical Practitioner or A Hospital Only