GCFER IS INJECTION

Iron Sucrose 20 mg Injection (5ml)

 

INDICATIONS OF IRON SUCROSE INJECTION

GCFER IS is indicated for the treatment of iron deficiency anemia in patients with chronic kidney disease (CKD).

SIDE EFFECTS OF IRON SUCROSE INJECTION

• GI irritation

• Epigastric pain

• Stomach cramping

• Constipation

• Nausea

• Vomiting

• Diarrhoea

• Dark stools

• Heart burn

• Discoloured urine

• Teeth staining

• IM: pain at inj site, abdominal pain at lower quadrant and local inflammation with inguinal lymphadenopathy.

• IV: Joint and muscle pain, bronchospasm, hypotension, tachycardia, flushing, sweating, dizziness.

• Potentially Fatal: Parenteral: Anaphylactoid reactions, circulatory collapse.

DRUG INTERACTIONS OF IRON SUCROSE INJECTION

Concurrent use with psychotropic drugs may worsen constipation. Increased systemic side effects with concomitant ACE inhibitors and parenteral iron admin.

CONTRAINDICATIONS OF IRON SUCROSE INJECTION

Hypersensitivity or intolerance to iron and overloading of iron in the body.

Anaemia not caused by iron deficiency.

Disturbances in iron utilisation, thalassemia.

Patients receiving repeated blood transfusion.

Parenteral: Iron overload, Ostler-Rendu-Weber syndrome, chronic polyarthritis, bronchial asthma, inflammation or infection of kidney or liver, uncontrolled hyperparathyroidism, decompensated liver cirrhosis. Pregnancy (1st trimester)

MECHANISM OF ACTION OF IRON SUCROSE INJECTION

Iron polymaltose is a water soluble, macro-molecular complex of iron (III) hydroxide and isomaltose. It is used in the treatment of iron-deficiency anaemia.

SPECIAL PRECAUTIONS OF IRON SUCROSE INJECTION

Avoid concomitant parenteral and oral iron admin, oral iron therapy should start at least 1 wk after last iron inj. Parenteral: Pregnancy (2nd and 3rd trimester), allergies, hepatic and liver insufficiency, low iron binding capacity and or folic acid deficiency. Facilities for CPR should be available during admin. Excessive IV infusion rate may cause nausea and epigastric upset. IV infusion route should be used only if IM route is unacceptable and when there is no stored iron in the bone marrow.

 

For Use of Registered Medical Practitioner or a Hospital Only.