ZUBISERT 50 Tablets

Sertraline Hydrochloride 50 mg { FC } Tablets

 

 

SERTRALINE HYDROCHLORIDE

It belongs to the class of SSRI (selective serotonin reuptake inhibitors) drug but is unrelated to other SSRIs. It is chemically unrelated to tricyclic, tetracyclic depressants. The mechanism of action is inhibition of CNS neuronal uptake of serotonin (5HT).

INDICATIONS OF SERTRALINE

Major depressive disorder. Obsessions and compulsion in patients with obsessive-compulsive disorder (OCD), panic disorder.

DOSAGE OF SERTRALINE

In depression & OCD: 50 mg once daily. Panic disorder: Initially 25 mg once daily and after 1 week 50 mg daily. Maximum dosage: 200 mg/day.

CONTRA-INDICATIONS OF SERTRALINE

Hypersensitivity, liver disease, MAOIs.

SPECIAL PRECAUTIONS OF SERTRALINE

Stop MAOI therapy at least 2 week prior to starting of sertraline. Renal/hepatic impairment, acute coronary syndromes, seizure disorders, concomitant use of alcohol. Paediatrics: Safety below 16 yrs not established. Pregnancy: Use if potential benefits outweigh the risk. Lactation: Use with cautions. Elderly: No special risk.

SIDE EFFECTS OF SERTRALINE

Dry mouth, nausea, stomach upset, diarrhoea, tremor, sweating, dizziness, sleeplessness, indigestion.

DRUG INTERACTIONS OF SERTRALINE

Warfarin, digoxin, cimetidine, lithium, MAOIs, tricyclic antidepressants, hypoglycaemic drugs, antipyrine, alcohol.

 

For Use of registered medical practitioner or a hospital only