Vildagliptin & Metformin Tablet Use,Side Effects,How work,Price...

GAMBOI M TABLET

Each Film Coated Tablet Contains:

Vildagliptin               50 mg

Metformin HCL IP  500 mg

How Metformin with Vildagliptin (GAMBOI M TABLET) Works

Metformin + Vildagliptin is a combination of two antidiabetic medicines:

Metformin and Vildagliptin. Metformin is an anti-diabetic medication (biguanide). It works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin. Vildagliptin is a DPP-4 inhibitor which works by increasing the release of insulin from the pancreas and decreasing the hormones that raise blood sugar levels. This reduces both fasting and postmeal sugar levels. Together, they provide better control of blood sugar.

Common Side Effects Of Metformin + Vildagliptin (GAMBOI M TABLET)

Nausea, Dizziness, Headache, Hypoglycemia (low blood glucose level), Tremors, Weight gain

 

VILDAGLIPTIN

Vildagliptin is an antidiabetic medicine used alone or in combination with other medicines to treat type 2 diabetes in adult patients.

Indications Of Vildagliptin

Type 2 diabetes mellitus

Dosage of Vildagliptin

Oral; 50mg to 100mg per day along with metformin or sulfonylurea.

Contra-Indications of Vildagliptin

Hypersensitivity

Special Precautions of Vildagliptin

Renal impairement

Side Effects of Vildagliptin

Hypoglycaemia, delayed gastric emptying, nausea and vomiting, flu-like symptoms, headache and dizziness may occur, stevens-johnson syndrome.

Drug Interactions of Vildagliptin

Risk of hypoglycemia with other anti-diabetic drug.

 

METFORMIN

They are completely different from the hypoglycaemic sulfonamides both in its structur and its mode of action. They cause little or no hypoglycaemia in non-diabetic. Possible mode of action suggested is that they interfere with mitochondrial respiratory chains-promote peripheral glucose utilization by enhancing anaerobic glycolysis or they enhance binding of insulin to its receptors & potentiate its action. Other explanation is that they suppress hepatic glucon-eogenesis & inhibit intestinal absorption of glucose.

Indication (Use) of Metformin :

• Non Insulin Dependent Diabetes.

• Maturity Onset (Non Insulin Dependent) Obese Diabetics In Whom Diet Alone Has Failed

• Maturity onset (non-insulin dependet) obese diabetics, in whom diet alone has failed. Very unstable juvenile or maturity onset (non-insulin dependent) diabetics, where a combination of insulin and metformin is beneficial. In those diabetics where sulphonylureas and metformin, when given alone fail but a combination works.

 

Contra-Indications of Metformin :

• Renal Failure

• Cardiovascular Collapse

• Diabetic Ketoacidosis

• Severe Hepatic In Sufficiency

• Hypersensitivity

• Pregnancy

• Lactation

Drug Interaction of Metformin :

• Insulin

• Other Oral Anti Diabetics

 

Side Effects of Metformin :

• Temporary Visual Impairment

• Abdominal Pain

• GI Disturbances

• Tolerance

• Hypoglycemia

• Lactic Acidosis

Packaging of Metformin Vildagliptin :

2*15 alu alu pack