SPINZ-500 Tablets          Cefadroxil IP 500mg Tablets

 

Like all b-lactams antibiotics it acts by selectively inhibiting the synthesis of muco-peptides in the bacterial cell wall of multiplying bacteria.

Indications of cefadroxil:

Urinary tract infections caused by E.coli, P. mirabilis and klebsiella spp. skin and skin structure infections caused by staphylococci and/or Streptococci: Pharyngitis and tonsillitis caused by Group A Beta-haemolytic streptococci.

Dosage of cefadroxil:

1-2 gm daily in two divided doses (500 mg to 1 gm every 12 hours) Children: 25-50 mg/kg body wt in divided doses every 12 hours.

Contra-Indications of cefadroxil:

Patients with any known allergy to cephalosporins

Special Precautions of cefadroxil :

Renal impairment, gastro intestinal disease, particularly colitis. Prolonged use can result in overgrowth of non-susceptible organisms. Use in pregnancy only if clearly indicated

Side Effects of cefadroxil :

Nausea, vomiting, diarrhoea, dysuria, pseudomembranous colitis. Allergies ((Rash, urticaria and Angiodema), genital pruritus, genital moniliasis, vaginitis and moderate transient neutropenia

Drug Interactions of cefadroxil:

Concurrent use with frusemide increases nephrotoxicity. Potentiates nephrotoxicity of aminoglycosides. Prothrombin time prolonged, caution necessary with anticoagulants. Probenecid prolongs half-life.