Deflazacort 12 mg Tablet Use, Indication, Side Effects, Dosage, Mechanism of Action, Price, Contra-Indications, Drug Interactions ....

BERICORT 12 TABLETS

Deflazacort 12 mg Tablet

Deflazacort is a corticosteroid used to treat various inflammatory and autoimmune conditions. It is often prescribed when other corticosteroids, like prednisone, are not well tolerated.

Uses & Indications of Bericort 12 Tablet:

Deflazacort is used to treat conditions such as:

• Inflammatory and autoimmune disorders: Rheumatoid arthritis, lupus, ulcerative colitis, Crohn’s disease

• Allergic reactions: Severe allergies, asthma

• Neurological diseases: Duchenne muscular dystrophy (DMD)

• Skin conditions: Eczema, psoriasis

• Organ transplantation: To prevent organ rejection

• Blood disorders: Certain types of anemia and platelet disorders

 

Mechanism of Action of Deflazacort 12 Tablet:

Deflazacort is a glucocorticoid that works by:

• Suppressing the immune system

• Reducing inflammation by inhibiting the release of inflammatory substances

• Preventing tissue damage from overactive immune responses

It gets converted into an active metabolite in the liver, which has similar effects to prednisone but with potentially fewer side effects on bone health and glucose metabolism.

 

Dosage of Bericort 12 Tablet:

Dosage depends on the condition being treated and the patient’s weight/response to therapy.

General Dosage Guidelines:

• Adults: 6–90 mg per day, depending on the condition

• Duchenne Muscular Dystrophy: 0.9 mg/kg per day

• Children: Doses are weight-based and should be prescribed by a doctor

• Elderly: Lower doses may be recommended due to potential side effects

It is best taken with food to reduce stomach irritation.

 

Side Effects of Bericort 12 Tablet:

Common side effects:

• Weight gain

• Increased appetite

• Insomnia

• Mood changes (anxiety, irritability)

• Indigestion

• Increased blood sugar levels

Serious side effects (long-term use or high doses):

• Osteoporosis (bone loss)

• Hypertension (high blood pressure)

• Cushing’s syndrome (moon face, fat redistribution)

• Glaucoma or cataracts

• Infections due to weakened immunity

• Growth suppression in children

 

Contraindications of Deflazacort 12 Tablet:

Deflazacort should not be used in:

• Active infections (e.g., tuberculosis, fungal infections)

• Uncontrolled diabetes

• Osteoporosis

• Peptic ulcers

• Severe psychiatric conditions (e.g., psychosis)

Caution is needed in pregnant and breastfeeding women only use if absolutely necessary.

 

Drug Interactions of Bericort 12 Tablet:

Deflazacort interacts with:

• NSAIDs (e.g., ibuprofen, aspirin): Increased risk of stomach ulcers

• Antidiabetic medications: May increase blood sugar levels

• Antihypertensives: Can raise blood pressure

• Live vaccines: Can reduce vaccine effectiveness and increase infection risk

• Antifungals (e.g., ketoconazole): May increase steroid levels in the blood

• Anticonvulsants (e.g., phenytoin, carbamazepine): May decrease effectiveness of Deflazacort

 

How Deflazacort 12 Tablet works