SERZON D Tablet

Diclofenac Potassium 50 mg,Serratiopeptidase 10 mg Enteric Coated Tablet 

 

USES OF DICLOFENAC 50MG + SERRATIOPEPTIDASE 10MG (serzon d tablet):

Used for painful conditions including

back pain

osteoarthritis

rheumatoid arthritis

osteoporosis

fibromyalgia

MECHANISM OF ACTION OF DICLOFENAC 50MG + SERRATIOPEPTIDASE 10MG(serzon d tablet):

Diclofenac has potent anti-inflammatory, analgesic and antipyretic actions. It inhibits the enzyme, cyclooxygenase, thus resulting in reduced synthesis of prostaglandin precursors. Absorption: Rapidly absorbed (oral solution, rectal suppository, IM); more slowly (enteric-coated tab).

SIDE EFFECTS OF DICLOFENAC 50MG + SERRATIOPEPTIDASE 10MG(serzon d tablet):

GI disturbances; headache, dizziness, rash; GI bleeding, peptic ulceration; abnormalities of kidney function. Pain and tissue damage.

DRUG INTERACTIONS OF DICLOFENAC 50MG + SERRATIOPEPTIDASE 10MG(serzon d tablet):

Not to be given IV to patients who are receiving other NSAIDs or anticoagulants including low dose heparin. Renal function may be worsened when used with ciclosporin or triamterene. Altered absorption when given with sucralfate, colestyramine or colestipol. Ophthalmic application of diclofenac may reduce the efficacy of ophthalmic acetylcholine and carbachol. Increased risk of GI ulceration and bleeding when used with corticosteroids, aspirin or anticoagulants.

CONTRAINDICATIONS OF DICLOFENAC 50MG + SERRATIOPEPTIDASE 10MG (serzon d tablet):

Active peptic ulcer; hypersensitivity to diclofenac or other NSAIDs. Treatment of perioperative pain in CABG surgery. 3rd trimester of pregnancy.

SPECIAL PRECAUTIONS FOR DICLOFENAC 50MG + SERRATIOPEPTIDASE 10MG(serzon d tablet):

History of GI ulceration; impaired cardiac, renal or hepatic function; hypertension; lactation. IV admin in patients with moderate or severe renal impairment; hypovolaemia or dehydration; asthma, porphyria. Monitor LFTs in patients on prolonged therapy. May prolong bleeding time; caution when used in patients with coagulation disorders or on anticoagulants. Prolonged therapy may increase risk of anaemia. 1st and 2nd trimester of pregnancy. Elderly, debilitated patients.

FOR USE OF REGISTERED MEDICAL PRACTITIONER OR A HOSPITAL ONLY