HETROFEN P Tablet
Aceclofenac With Paracetamol Tablet Use, Dosage, Side Effects, Drug Interactions, Mechanism Of Action, Mechanism Of Action, Price…
HETROFEN P Tablet
Aceclofenac 100 Mg, Paracetamol 325 Mg Tablet
Anti-Inflammatory Painkillers Like Aceclofenac Are Also Called Non-Steroidal Anti-Inflammatory Drugs (Nsaids), Or Sometimes Just 'Anti-Inflammatories'. Aceclofenac Is Prescribed For People With Painful Rheumatic Conditions Such As Osteoarthritis, Rheumatoid Arthritis And Ankylosing Spondylitis. It Eases Pain And Reduces Inflammation.
Aceclofenac With Paracetamol Tablet (Hetrofen P) Uses
Hetrofen P Tablet Is Used For Pain Relief.
Is Prescribed For Fever, Various Kinds Of Pain And Arthritis
How Aceclofenac + Paracetamol (Hetrofen P) Works :
Aceclofenac + Paracetamol Is A Combination Of Two Medicines: Aceclofenac And Paracetamol. These Medicines Work By Blocking The Action Of Chemical Messengers Responsible For Pain, Fever And Inflammation (Redness And Swelling).
Side Effects Of Aceclofenac 100mg + Paracetamol 325mg Tablet (Hetrofen P) :
Nausea, Diarrhea, Dizziness, Drowsiness, Dyspepsia, Abdominal Pain, Increased Liver Enzymes
Drug Interactions Of Aceclofenac and Paracetamol Tablet (Hetrofen P) :
Paracetamol: Reduced Absorption Of Cholestyramine Within 1 Hr Of Administration.
Accelerated Absorption With Metoclopramide. Aceclofenac
Increased Nephrotoxicity With Diuretics.
Serum-Potassium Should Be Monitored When Used With Potassium-Sparing Diuretics.
May Enhance Activity Of Anticoagulants.
Contra indications Of Aceclofenac With Paracetamol Tablet (Hetrofen P) :
Hypersensitivity. Moderate To Severe Renal Or Hepatic Impairment; Severe Heart Failure; Pregnancy (Third Trimester).
Mechanism Of Action Of Aceclofenac and Paracetamol (Hetrofen P) :
Aceclofenac is a Phenylacetic Acid Derivative That Inhibits Synthesis Of The Inflammatory Cytokines Interleukin-1b And Tumour Necrosis Factor, And Inhibits Prostaglandin E2 Production. It Increases Glycosaminoglycans (GAG) Synthesis, The Principal Macromolecule Of The Extracellular Matrix, Which Aids In Repair and Regeneration of Articular Cartilage. Thus, Aceclofenac Has +Ve Effects on Cartilage Anabolism Combined with Modulating Effect of Matrix Catabolism.
Paracetamol Has Analgesic And Antipyretic Action With Weak Anti-Inflammatory Activity. It Produces Analgesia By Increasing Pain Threshold And Antipyresis By Acting On The Hypothalamic Heat-Regulating Centre.
Special Precautions For Aceclofenac 100mg + Paracetamol 325mg (Hetrofen P) :
GI Disease; Renal Or Hepatic Impairment; Alcohol-Dependent Patients; Asthma Or Allergic Disorders; Haemorrhagic Disorders; Hypertension; Cardiac Impairment. Elderly. Caution When Driving Or Operating Machinery. Monitor Renal And Hepatic Function And Blood Counts During Long Term Treatment. Persistently Elevated Hepatic Enzyme Levels May Require Drug Withdrawal. Pregnancy, Lactation.
For Use of Registered Medical Practitioner or A Hospital Only
